Del 23 - Advances in Molecular and Cell Biology

Ion Pumps, Part A

Inbunden, Engelska, 1997

AvJ.P. Andersen,Denmark) Andersen, J.P. (Institute of Physiology, University of Aarhus, Aarhus,J. P. Andersen,J P Andersen

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Both eukaryotic and prokaryotic cells depend strongly on the function of ion pumps present in their membranes. The term ion pump, synonymous with active ion-transport system, refers to a membrane-associated protein that translocates ions uphill against an electrochemical potential gradient. Primary ion pumps utilize energy derived from chemical reactions or from the absorption of light, while secondary ion pumps derive the energy for uphill movement of one ionic species from the downhill movement of another species.

In the present volume, various aspects of ion pump structure, mechanism, and regulation are treated using mostly the ion-transporting ATPases as examples. One chapter has been devoted to a secondary ion pump, the Na⁺-Ca²⁺ exchanger, not only because of the vital role played by this transport system in regulation of cardiac contractility, but also because it exemplifies the interesting mechanistic and structural similarities between primary and secondary pumps.

Produktinformation

Utgivningsdatum1997-11-19
Mått152 x 229 x 0 mm
Vikt1 210 g
FormatInbunden
SpråkEngelska
SerieAdvances in Molecular and Cell Biology
Antal sidor248
FörlagElsevier Science
ISBN9780762302871

Tillhör följande kategorier

Biologi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik
Hematologi inom Medicin
Tillämpad fysik inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik

Preface (J.P. Andersen). Reaction Mechanism of the Sarcoplasmic Recticulum Ca2+-ATPase (H. Wolser, S. Engelender, and L. de Meis). The ATP Binding Sites of P-Type Ion Transport ATPases: Properties, Structure, Conformations, and Mechanism of Energy Coupling (D.B. McIntosh). The Gastric H+-K+-ATPase (J.M. Shin, D. Bayle, K. Bamberg and G. Sachs). Genetic Approaches to Structure-Function Analysis in the Yeast Plasma Membrane H+-ATPase (D.S. Perlin and J.E. Haber). Copper Homeostatsi by CPX-Type ATPases: The New Subclass of Heavy Metal P-Type ATPases (M. Solioz). Isosform Diversity and Regulation of Organellar-Type Ca2+-Transport ATPases (F. Wuytack, L. Raeymaekers, J. Eggermont, L. Van Den Bosch, H. Verboornen, and L. Mertens).

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