Intensity-Modulated Radiation Therapy

Steve Webb, Professor of Radiological Physics, Head, Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Trust, Sutton, Surrey, UK

• PREFACE 1 IMRT: GENERAL CONSIDERATIONS 1.1 Background to the development of IMRT 1.2 How many IMBs are needed and where should they be placed?—the use of compensators 2 ROTATION IMRT: TOMOTHERAPY 2.1 NOMOS MIMiC delivery 2.2 Developments in IMRT using the NOMOS equipment reported 2.3 The tomotherapy machine at the University of Wisconsin 2.4 Verification of IMRT by the NOMOS MIMiC and the Wisconsin machine 3 IMRT USING A MULTILEAF COLLIMATOR 3.1 IMB delivery using a multileaf collimator 3.2 Issues in delivering IMBs via the DMLC technique 3.3 Delivery of IMRT by the multiple-static-field technique 3.4 IMRT by scanned beams 3.5 Combined electron and photon IMRT 3.6 Summary 4 IMRT: CLINICAL IMPLEMENTATION AND ASSOCIATED ISSUES 4.1 Clinical applications of IMRT 4.2 IMRT and movement 4.3 Induced cancers from IMRT? 4.4 Verification of IMRT 4.5 Potential limitations for CFRT with IMRT 4.6 A look to the future—robotic IMRT? 4.7 Summary 5 3D PLANNING FOR CFRT INCLUDING IMRT 5.1 A philosophical note on the optimization (customization?) of treatments 5.2 PTV determination, fuzzy logic and adaptive radiation therapy 5.3 Multimodality imaging and therapy planning 5.4 Plan improvement—‘conventional’ CFRT, neural nets 5.5 Optimization of IMRT 5.6 Choice of optimization technique 5.7 Beam-orientation optimization 5.8 Organ motion and treatment outcome 5.9 Analysis of treatment plans 5.10 Automatic importance factors 5.11 Summary and a look to the future

"It would be a very useful book for graduate students and researchers in many disciplines including medical physics, biomedical engineering, radiology, radiotherapy and clinical research. Intensity-Modulated Radiation Therapy is recommended for all health science libraries as well as science libraries."-E-STREAMS, Vol. 5, No. 12