This book constitutes the refereed proceedings of the Second International Symposium on Intelligent Technology for Future Transportation, ITFT 2025 held in London, UK, during November 18–20, 2025.The 26 full papers included in this volume were carefully reviewed and selected from 67 submissions. They are organized into the following topical sections: Intelligent Transportation Systems and Data-Driven Modeling & Optimization; Intelligent Vehicles, Autonomous Control, and Perception Technologies; Smart Transportation Infrastructure, Safety, and Resilience; and Transportation Electrification, Energy Systems, and Grid Integration.