This compendium brings together leading researchers in the fields of Intelligent Systems and healthcare aiming at medical engineers, healthcare managers and computer scientists worldwide. This book is an overview of intelligent paradigms and strategic investments that might payoff for the healthcare enterprise. Specifically, the reader will get ideas for efficiency enhancements for improving effectiveness and quality of care and for increasing patient safety. "Advanced Intelligent Paradigms in Healthcare" straddles technologic topics from DNA processing and automating medical second opinions in the lab, to telemedicine and chat spaces for rural patient outreach, among many others. In terms of management concerns, this book also explores systems approaches such as automated clinical guidelines, institutional workflow management, and best practices and lessons learned with actual applications.