This book introduces the core framework of Intelligent Manufacturing Engineering—an emerging STEM discipline that integrates mechanical engineering, operations research, and AI. It defines the field through three key pillars: relationships as its essence, Deep Operations Research as its logic, and a new guidelines as its outcome.As the first monograph on Intelligent Manufacturing Engineering, the book offers intuitive logic, concise algorithms, and accessible mathematical reasoning. It is ideal for students in engineering, mathematics, and computer science, and serves as a valuable reference for professionals engaged in intelligent manufacturing system R&D.