Inbunden, Engelska, 2027

Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease

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Beskrivning

Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphasizing the critical need for early detection methods prior to the onset of microalbuminuria. The book's primary focus is on the study of pseudoesterase activity in urinary albumin and other proteins as a potential biomarker for early diagnosis of diabetic kidney disease. This resource bridges a significant gap in current literature by providing an in-depth analysis of how this enzymatic activity can inform the classification and management of diabetic nephropathy.

Chapters cover foundational knowledge of diabetes and its complications, the mechanisms of diabetic nephropathy, and detailed discussions on human serum albumin and its enzymatic activities. Each chapter covers the biochemical characterization of pseudoesterase activity, methods for its detection, and the significance of urinary proteomic profiling. Final chapters highlight future research opportunities and the potential for developing point-of-care testing tools, positioning this work as a critical resource for advancing the field of diabetic kidney disease research and clinical practice.

Describes, in detail, the pseudo esterase activity of human serum albumin as a novel classifier of diabetic nephropathy
Provides the latest research developments on the importance of urinary proteins with enzymatic activities as a biomarker for diabetic kidney disease discovered by a team of researchers
Offers insights into experimental planning, potential research topics, and the implications of early detection strategies for improved patient outcomes

Produktinformation

Utgivningsdatum: 2027-03-01
Mått: 191 x 235 x undefined mm
Vikt: 450 g
Format: Inbunden
Språk: Engelska
Antal sidor: 300
Förlag: Elsevier Science
ISBN: 9780443455704

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Mer information

Dr Dibyajyoti Banerjee passed MBBS from North Bengal Medical College, Darjeeling, West Bengal, India in 1999 with Honors in Physiology and Biochemistry and a Gold Medal in Pathology. He was awarded an MD (Biochemistry) from Kasturba Medical College, Manipal, Karnataka, India in 2003. During the study of MD(Course), he established urinary hydrogen peroxide as a biomarker of malignancies. He is an expert in biochemistry in with research expertise in human serum albumin and POCT development. Currently, he is interested in the esterase activity of albumin and recently while working as Professor and Head, of the Department of Experimental Medicine and Biotechnology at the Postgraduate Institute of Medical Education and Research, Chandigarh, India his team discovered that pseudo esterase activity of human serum albumin has the potential to screen microalbuminuria for diagnosis of diabetic nephropathy. He has over 10 years of research experience and published ~40 articles. Dr Deepak Kumar, PhD is Assistant Professor at the School of Bioengineering and Food Technology, Faculty of Applied Sciences and Biotechnology, Shoolini University, Himachal Pradesh, India, and holds a concurrent appointment as Project Research Scientist-III at the Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh. His research focuses on biomarker discovery, point-of-care tool development, enzymology, microalbuminuria, and molecular toxicology, with particular emphasis on the pseudoesterase activity of human serum albumin.Dr Kumar is a lifetime member of the Association of Clinical Biochemists of India and actively reviews manuscripts for journals including Clinica Chimica Acta and Scientific Reports. His research has appeared in Clinica Chimica Acta, Talanta, Analytical Biochemistry, and Advances in Clinical Chemistry. He received a Certificate of Appreciation in the Innovation Category from PGIMER, Chandigarh in 2025.

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