Innovation in Anesthesiology

Dr Adam E. M. Eltorai, MD, PhD completed his graduate studies in Biomedical Engineering and Biotechnology along with his medical degree from Brown University. His work has spanned the translational spectrum with a focus on medical technology innovation and development. Dr. Eltorai has published numerous articles and books.Nancy Patterson is a Venture Analyst and the President and CEO and Founder of Strategy Inc. (in 2000), a lifescience market analysis and valuation company for US and International clients. She has over 18 years’ experience in senior business development and marketing roles with emerging technology medical device companies. Patterson is an immunologist from University of Michigan and also has an MBA from University of Southern California.Dr. Ashley Szabo Eltorai is a staff physician in Anesthesiology and Critical Care at the YaleNew Haven Hospital. She is also an Assistant Professor in the School of Medicine at Yale University. Dr. Szabo Eltorai received her M.D. at the Case Western Reserve UniversitySchool of Medicine. She is a member of the American Society of Anesthesiologists and the Society of Critical Care Anesthesiology. Dr. Piyush Mathur is a Staff Anesthesiologist and Intensivist at The Cleveland Clinic. Since 2015, he has been the Program director of the Anesthesia Critical Care Fellowship Program at The Cleveland Clinic. Dr. Mathur received his MBBS from the Armed Forced Medical College and completed subsequent fellowships at The Cleveland Clinic in Critical Care Medicine.

• 1 Introduction—overview and innovation process flow diagram2 Technology in anesthesia and perioperative medicine: exploring opportunities and challenges3 Specific opportunities for innovation in anesthesia4 Validate, refine, and define the problem to be solved5 Market analysis—the anesthesia market landsc6 Competitive analysis7 Product requirements for emerging anesthesia technologies8 Partner with a successful expert9 Conceptualizing idea to solution10 Prior art searching11 Patent strategy—patent types and timing12 Concept testing and selection—where and why will it fail13 What to prototype?14 Medical device development15 Pilot study16 Clinical research17 Licensinghow to, terms, expectations, examples for university technology transfer18 Funding approaches—why, from where, how much, terms19 Personnel—teams needed, roles20 Physician entrepreneurship—three steps to success21 Choosing an entity structure for your business22 FDA regulation of anesthesia and critical care medical devices23 Step-by-step guide for Food and Drug Administration listing, 510(k), premarket approval24 Anesthesia reimbursement25 Business models26 Marketing, sales, and distribution27 Business strategy—valuing emerging technology companies28 Business operations29 Post launch physician relationships30 Innovation in anesthesiology: technology development and commercialization handbook31 From idea to commercialization: development of a breathing-controlled gaming device for pediatric anesthesia induction32 Case study: improve the safety and compliance of drug preparation and administration with barcode technology33 Revolutionizing blood transfusion: HemaLogiX-optimizing clinical appropriateness and resource utilization34 FirstLook LTA from Guidance Airway Solut