This volume contains the proceedings of the thirteenthbiennial International Conference on Information Processingin Medical Imaging (IPMI XIII), held on the campus ofNorthern Arizona University in Flagstaff, Arizona, in June1993. This conference was the latest in a series of meetingswhere new developments in the acquisition, analysis andutilization of medical images are presented, discussed,dissected, and extended. Today IPMI is widely recognized asa preeminent international forum for presentation ofcutting-edge research in medical imaging and imageanalysis.The volume contains the text of the papers presented orallyatIPMI XIII. Over 100 manuscripts were submitted andcritically reviewed, of which 35 were selected forpresentation. In this volume they are arranged into ninecategories: shape description with deformable models,abstractshape description, knowledge-based systems, neuralnetworks, novel imaging methods, tomographic reconstruction,image sequences, statistical pattern recognition, and imagequality.