In Vivo EPR (ESR)

Theory and Application

Inbunden, Engelska, 2003

2 749 kr

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A textbook on a relatively new subject in biomedical electron spin resonance. While a few chapters have appeared in special topics volumes in this series, this book covers the principles and theory, instrumentation, as well as the latest applications at the time of its writing. The authors are experts in their fields. The book is divided into two major sections dealing with theory and instrumentation, and aspects of biochemistry, in vitro and in vivo applications. A significant amount of detail is devoted to clinical applications and the problems and pitfalls encountered in in vivo spectroscopy and imaging.

Produktinformation

Utgivningsdatum2003-11-30
Mått155 x 235 x 47 mm
Vikt1 260 g
FormatInbunden
SpråkEngelska
SerieBiological Magnetic Resonance
Antal sidor656
Upplaga2003
FörlagSpringer Science+Business Media
ISBN9780306477904

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1 Introduction to in Vivo EPR.- 1. Aim and Scope of the Book.- 2. Rationale for in Vivo EPR.- 3. Challenges of in Vivo EPR.- 4. Types of Paramagnetic Species Observable with in Vivo EPR.- 5. Types of Instrumental Approaches Used for in Vivo EPR.- 6. Experiments with Animals.- 7. Conclusions and a Look to the Future.- 8. The Nomenclature of Biomedical EPR—Reducing the Confusion.- 9. References.- Section I. Theory and Instrumentation.- 2 Principles of in Vivo EPR.- 3 Frequency and Power Considerations for in Vivo EPR and Related Techniques.- 4 CW EPR Signal Detection Bridges.- 5 Resonators for Low-Field in Vivo EPR.- 6 Principles of Imaging.- 7 Time-Domain Radio Frequency EPR Imaging.- Section II. Biochemical Applications: Biochemistry and Biophysics.- 8 Stable Soluble Paramagnetic Compounds.- 9 Stable Particulate Paramagnetic Materials as Oxygen Sensors in EPR Oximetry: Coals, Lithium Phthalocyanine, and Carbon Chars.- 10 Packaging of Paramagnetic Materials in Oximetry and Other Applications.- 11 Spin Trapping in Vivo: Facts and Artifacts.- 12 Ex Vivo Detection of Free Radical Metabolites of Toxic Chemicals and Drugs by Spin Trapping.- 13 Chemistry and Biology of Nitric Oxide.- 14 In Vivo and in Vitro Detection of NO by EPR.- 15 The Measurement of Oxygen in Vivo Using EPR Techniques.- 16 Cardiac Applications of in Vivo EPR Spectroscopy and Imaging.- 17 Applications of in Vivo EPR Spectroscopy and Imaging in Cancer Research.- 18 Applications of in Vivo EPR Spectroscopy and Imaging to Skin.- 19 Pharmaceutical Applications of in Vivo EPR.- 20 Proton-Electron Double-Resonance Imaging (PEDRI).- 21 Combining NMR and EPR/ESR for in Vivo Experiments.- 22 Potential Medical (Clinical) Applications of EPR: Overview and Perspectives.- of Previous Volumes.