Impact of Food Bioactives on Health

in vitro and ex vivo models

Inbunden, Engelska, 2015

Av Kitty Verhoeckx, Paul Cotter, Iván López-Expósito, Charlotte Kleiveland, Tor Lea, Alan Mackie, Teresa Requena, Dominika Swiatecka, Harry Wichers, Ivan Lopez-Exposito

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“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011.

Produktinformation

Utgivningsdatum2015-05-19
Mått155 x 235 x 27 mm
Vikt708 g
FormatInbunden
SpråkEngelska
Antal sidor338
FörlagSpringer International Publishing AG
ISBN9783319157917

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Tillverkningsteknik inom Naturvetenskap och teknik

Introduction.- Gastrointestinal digestion models, general introduction.- Static digestion models general introduction.- InfoGest consensus method.- Approaches to static digestion models.- Dynamic digestion models general introduction.- The TNO gastro-Intestinal Model (TIM).- Dynamic Gastric Model (DGM).- Human Gastric Simulator (Riddet model).- The DIDGI® System.- General introduction to cells, cell lines and cell culture.- Epithelial cell models; General introduction.- Caco-2 cell line.- HT29 cell line.- The IPEC-J2 cell line.- Co-cultivation of Caco-2 and HT-29MT.- Innate and adaptive immune cells; General introduction.- THP-1 and U937 cells.- Peripheral blood mononuclear cells.- PBMC-derived T cells.- Dendritic Cells.- Co-culture Caco-2/ immune cells.- Enteroendocrine Cell Models: General introduction.- STC-1 cells.- NCI-H716 cells.- Murine GLUTag cells.- In vitro intestinal tissue models: General introduction.- Intestinal crypt organoids as experimental models.- Porcine ex vivointestinal segment model.- Ussing chamber.- In vitro fermentation models: General Introduction.- One compartment fermentation model.- The TNO in vitro model of the colon - TIM-2.- The Simulator of the Human Intestinal Microbial Ecosystem – SHIME®.- The computer-controlled multicompartmental dynamic model of the gastrointestinal system SIMGI.