Immunology

Ian Todd, MA, PhD, FHEA, is Associate Professor and Reader in Cellular Immunopathology, University of Nottingham, School of Life Sciences, Queen's Medical Centre, Nottingham.Gavin Spickett, MA, LLM DPhil, BM BCh, FRCPath, FRCP, FRCPE, is Consultant and Senior Lecturer in Clinical Immunology, Royal Victoria Infirmary, Newcastle upon Tyne.Lucy Fairclough, BSc, MSc, PhD, is Assistant Professor in Immunology, University of Nottingham, School of Life Sciences, Queen's Medical Centre, Nottingham.

• Preface to the seventh edition viiFrom the preface to the first edition viiiKey to symbols used in this edition ixOverview of the immune system xPart 1 Immunity and the Immune System1 The nature of immunity 32 Immune recognition 143 Lymphocyte development and activation 344 Lymphocyte interactions, cytokines and the lymphoid system 455 Immunoglobulins 636 Complement 797 Phagocytes 878 Mast cells, basophils and eosinophils 949 Killer cells 101Part 2 Immunopathology10 Immunity and infection 11111 Primary and secondary immunodeficiency disorders 12612 The generation of tissue‐damaging responses 14813 Mechanisms of immunological tissue damage 16714 Lymphoproliferative disease 17915 Transplantation 19116 Immunological therapy 203Part 3 Self-assessment: answersSelf-assessment: answers 215Index 221

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