Immune Mechanisms in Inflammatory Bowel Disease

• Structure and Function of the Gut Mucosal Immune System.- Functional Aspects of the Mucosal Immune System.- Recent Progress in Inflammatory Bowel Disease Genetics.- Microbial and Dietary Factors in the Pathogenesis of Chronic, Immune-Mediated Intestinal Inflammation.- Experimental Models of Mucosal Inflammation.- Overview of Role of the Immune System in the Pathogenesis of Inflammatory Bowel Disease.- The Role of the Epithelial Barrier in Inflammatory Bowel Disease.- Involvement of Dendritic Cells in the Pathogenesis of Inflammatory Bowel Disease.- Alterations of T Lymphocytes in Inflammatory Bowel Diseases.- The B-Cell System in Inflammatory Bowel Disease.- Alterations of Mesenchymal and Endothelial Cells in Inflammatory Bowel Diseases.- Role of Mast Cells and Eosinophils in Neuroimmune Interactions Regulating Mucosal Inflammation in Inflammatory Bowel Disease.- Multiparameter Analysis of Immunogenetic Mechanisms in Clinical Diagnosis and Management of Inflammatory Bowel Disease.- The Role of Probiotics and Antibiotics in Regulating Mucosal Inflammation.- From Immunogenic Mechanisms to Novel Therapeutic Approaches in Inflammatory Bowel Disease.

From the reviews: "This multi-author book ... provides a complete overview about intestinal immunology, thanks to the contribution of many of the leaders in this field. ... The completeness of ... articles allows the reader to consult the book rapidly in order to achieve direct information about the specific aspect he is interested in. This book can be recommended to both researchers interested in basic aspects of inflammatory bowel disease and clinical gastroenterologists who want to raise their awareness of the mechanisms underlying clinical manifestations ... ." (A. Cassinotti, Digestive and Liver Disease, Vol. 39, 2007)