Immune Infertility

The Impact of Immune Reactions on Human Infertility

Häftad, Engelska, 2014

Av Walter K.H. Krause, Rajesh K. Naz, Walter K. H. Krause

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Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell.

Produktinformation

Utgivningsdatum2014-12-13
Mått155 x 235 x 14 mm
Vikt382 g
FormatHäftad
SpråkEngelska
Antal sidor236
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783642422867

Tillhör följande kategorier

Sperm Antigens.- Proteomics of Human Spermatozoa.- Methods of Analysis of Sperm Antigens Related to Fertility.- Sperm Surface Proteomics.- Sperm Functions Influenced by Immune Reactions.- Antisperm Antibodies (ASA).- The Immune Privilege of the Testis.- Immune Chemistry of ASA.- Sperm-Specific T Lymphocytes.- Site and Risk Factors of Antisperm Antibodies Production in the Male Population.- Biologic Substrates Containing ASA.- ASA in the Female.- Sperm-Immobilizing Antibody and Its Target Antigen (CD52).- The Clinical Impact of Sperm Antibodies.- Male Autoimmune Infertility.- Tests for Sperm Antibodies.- Impact on Fertility Outcome.- Sperm Antibodies and Assisted Reproduction.- Treatment of Immune Infertility.- Immune Contraception.- Immunization with Sperm Antigens to Induce Contraception.- Immunocontraception in Wildlife Animals.- Experience from Clinical Trials with Fertility Control Vaccines.

From the reviews: "The authors direct their work to clinicians, scientists, trainees in reproductive biology, obstetricians/gynecologists, and urologists. ... This highly specialized field is clearly depicted with the aid of graphs, tables, schematic diagrams, and exquisite photomicrographs. ... This is a unique, comprehensive, and cogent update of basic and therapeutic advances in the field of immunoinfertility." (Irvin H. Hirsch, Doody's Review Service, December, 2009)