Human Organs-on-a-Chip Technology

Häftad, Engelska, 2024

Av Mohanan,P.V, P.V. Mohanan, India) Mohanan, P.V., PhD (Scientist-G and Head, Toxicology Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India, P. V. Mohanan

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Human Organs-on-a-Chip Technology focuses on technology advancement from “organ-on-a-chip”, “multi organs-on-a-chip”, and the newest stage of “human organs-on-a-chip." Chapters investigate the design, simulation studies, device development, and application of microfluidic systems. In addition, they offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices, and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research.

Explores organs-on-a-chip technology, from the basics, to advanced developments and existing challenges and recent research trends and applications
Reviews every aspect of microfluidic devices, including biological evaluation and targeted delivery
Includes the latest information on regulatory updates

Produktinformation

Utgivningsdatum2024-06-18
Mått191 x 235 x undefined mm
Vikt1 270 g
FormatHäftad
SpråkEngelska
Antal sidor628
FörlagElsevier Science
ISBN9780443137822

Tillhör följande kategorier

Biokemisk teknik inom Naturvetenskap och teknik
Biomedicinsk teknik inom Medicin

Dr. Mohanan FNASc, is the Head of the Division of Toxicology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (Govt. of India). He is a visiting professor and visiting researcher at Toyo University, Japan and a Certified Biological Safety Specialist. Previously, he was a JSPS Post doctoral Fellow at the University of Tsukuba, Japan in the field of Neurotoxicity. He joined Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Govt. of India in 1989 and has spent 33 years of professional life working there. As a toxicologist he has been intimately associated with all the medical devices/technologies developed at SCTIMST. He received the lifetime achievement award from the Society of Toxicology India, for the outstanding contribution in the field of toxicology. He also patented an ELISA kit for the measurement of pyrogenicity. Mohanan made significant contributions for the development of medical device regulations in India. He has authored 231 publications and edited 6 books. Presently he is the secretary general of the Society of Toxicology, India.

1. Basics of Microfluidics technology2. The Physics and Engineering of Flow in Organ on a Chip Devices3. Importance of Soft lithography4. Development of microfluidic devices5. Microfluidics based point of care devices6. Microfluidics, Organs-on-a-chip and 3D printing7.Microfluidic platforms: applications and challenges8. Design and simulation study of Organ-on-a-chip9. Primary Cell culture for Organ-on-a-chip10. Vascularisation in organs-on-a-chip11. Organ-on-a-chip in nanotechnology12. Organs-on-a-chip in precision medicine13. Foeto-placental organ-on-a-chip14. Organs-on-a-chip in drug development15. Organ-on-a-chip for multianalyte monitoring16. Organ-on-a-chip for Blood-brain-barrier studies17. Organs on a chip models for sensor18. Innovative ‘organs-on-a-chip’ technology for marine drug development19. Exposure-on-a-chip as a model for inhalation toxicology and pharmacology research20. Brain-on-chip21. Recent breakthrough in organ-on-a-chip22. 3D printed microfluidic chips23. 3D tissue and Organ-on-a-chip models24. Vascularisation of organoids in microfluidic chips25. Multiorgans-on-a-chip: Design and applications26. Multiorgans-on-a-chip for subacute toxicity27. Multiorgans-on-a-chip for acute toxicity28. Human organs-on-a-chip for biological evaluation29. Human organs-on-a-chip for cancer modelling