Human iPSC-derived Disease Models for Drug Discovery

Inbunden, Engelska, 2023

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Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research.

Produktinformation

Utgivningsdatum2023-11-24
Mått155 x 235 x 23 mm
Vikt738 g
FormatInbunden
SpråkEngelska
SerieHandbook of Experimental Pharmacology
Antal sidor332
FörlagSpringer International Publishing AG
ISBN9783031423482

Tillhör följande kategorier

Biokemisk teknik inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik
Regenerativ medicin inom Medicin
Farmakologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Part 1 General considerations.- Human iPS for clinical applications and cellular products.- 3D-printed iPS disease models.- Part 2 CNS iPSC and organoids.- iPS-derived neurons and brain organoids from patients (brain).- iPS-derived RGCs (eye).- iPS-derived glia (brain).- iPSC to model blood-brain barrier endothelial cells.- Part 3 iPSC-derived nociceptive neurons.- IPSC-based peripheral nerve modeling.- Part 4 Non-neuronal specialized cell types.- iPSC-based drug screening of differentiated cardiomyocyte subtypes.- iPSC-based cardiac disease modeling: from cell to tissue.- iPSC-derived corneal endothelial cell.- iPSC-derived trabecular meshwork (eye).- iPSC for in vitro disease modeling of diabetes.