Heterocyclic Compounds as Pharmaceutical Ingredients

Divya Bajpai Tripathy, PhD is a Professor in the Department of Chemistry in?the School of Basic and Applied Sciences at Galgotias University with more than 15 years of experience in teaching, research, and academic leadership. She has published more than 130 peer-reviewed research papers, authored and edited 11 books, and contributed more than 35 book chapters. Her research focuses on interdisciplinary applications of chemistry in healthcare, environmental remediation, advanced materials, and biomedical technologies.Priyanka Chhabra, PhD is an Assistant Professor in the Amity Institute of Biotechnology at Amity University, with a background spanning teaching, research, and industry in biotechnology and allied fields.Anjali Gupta, PhD is a Professor in the Department of Chemistry at Galgotias University. She has authored influential research and review articles and served as a principal investigator on multiple projects. Her research focuses on biomaterials, MOF-based materials, anti-corrosive coatings, water remediation, and bioactive compounds.

• Preface xvii1 Heterocyclic Molecules as an Active Pharmaceutical Ingredient: An Introduction 1Anushka Sharma, Awaneet Kaur, Pranav Gupta, Debashis Paramanick and Abdulsalam Alhalmi2 Biologically Active Nitrogen Heterocyclic Compounds 27Diwakar Chauhan, Monika Chauhan, Priya Tyagi and Amrita Kaushik3 Heterocyclic Compounds as Antimicrobial (Antibacterial, Antifungal, Antiviral, and Anthelmintics) Agent 61Gaurank Pal, Devaang Mathur, Lakshit Srivastav, Vishal Mehare, Ajay Gupta, Shruti Khanna Ahuja and Puja Prasad4 Heterocyclic Compounds as Anticancer Agents 123Aadya Singh, Priyanshi Kamboj, Pragya Swami, Puja Prasad and Shruti Khanna Ahuja5 Heterocyclic Compounds as Anti-Inflammatory Agents 179Hemlata Nimesh, Sagar Kumar and Nidhi Srivastava6 Heterocyclic Compounds as Antioxidant Agents 207Niranjan Kaushik, Shristi Singh, Ajita Paliwal and Sachin Chaudhary7 Heterocyclic Compounds as Anticonvulsants, Antipyretics, Antiallergic Agents, and Antileprosy Agents 249Anushka Sharma, Awaneet Kaur, Pranav Gupta, Debashis Paramanick and Abdulsalam Alhalmi8 Heterocyclic Compounds as Antihistamine Agents 269Avinash Jha, Saurabh Sharma, Deepika Paliwal, Aman Thakur and Saurabh Srivasatva9 Heterocyclic Compound Having Herbicides Activity 307Niranjan Kaushik, Mridul Singh Sengar, Deepika Paliwal and Nadeem Ahmad Siddique10 Heterocyclic Compounds as Antihypertensive Agents 349Manjot Singh, Deepika Paliwal, Aman Thakur, Manvi Karayat and Saurabh Srivasatva11 In Silico Studies on Heterocyclics as an Active Pharmaceutical Agent 389Anurag Paul, Debanjali Adhikary, Abdul Kareem Parchur, Gayatri Sharma and Apoorva Mishra12 Piperazine Derivatives: Potential Antimicrobial Agents 407R. Prathap, Rashmi Dubey, Anjali Gupta and Divya Bajpai Tripathy13 Synthetic Drug Discovery Strategy of Benzimidazole Derivatives and Their Applications 443Prasad Vijay Korake, Diwakar Chauhan and Subhalaxmi Pradhan14 Synthesis and Biological Evaluation of Thiophene- and Piperazine-Based Active Compounds 475Ayyagari Subramanya Sharma, Subhalaxmi Pradhan and Prashant Kumar15 Heterocyclic Compounds as Antileprotic Agents 509Sanjita Das, Anjali Singh, Shalini Gautam and Gyas Khan16 Bromodomains: Biomedical Applications of Active Ingredients 531Sweta Raj, Anjan Kumar Nayak, Harsh Vardhan and Divya Bajpai TripathyReferences 543Index 547