Hereditary Breast and Ovarian Cancer

Molecular Mechanism and Clinical Practice

Häftad, Engelska, 2022

Av Seigo Nakamura, Daisuke Aoki, Yoshio Miki

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This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease.

Produktinformation

Utgivningsdatum2022-10-22
Mått155 x 235 x 17 mm
Vikt565 g
FormatHäftad
SpråkEngelska
Antal sidor324
FörlagSpringer Verlag, Singapore
ISBN9789811645235

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Onkologisk kirurgi inom Medicin
Onkologi inom Medicin
Biologi inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Klinisk medicin och internmedicin inom Medicin
Kirurgi inom Medicin

1 History, Advancements, and Future Strategies.- 2 Molecular basis of BRCA1 and BRCA2 - Homologous recombination deficiency and tissue-specific carcinogenesis.- 3 Genetic Testing.- 4 Variants of uncertain significances in hereditary breast and ovarian cancer.- 5 Genetic counseling in Hereditary Breast and Ovarian Cancer.- 6 Hereditary Breast Cancer.- 7 Hereditary Ovarian Cancer.- 8 Risk-Based Breast Cancer Screening.- 9 Chemoprevention for Breast Cancer.- 10 Chemoprevention for Ovarian Cancer.- 11 Risk-Reducing Mastectomy (RRM).- 12 Risk-reducing salpingo-oophorectomy (RRSO).- 13 Panel Testing.- 14 Germline Findings through Precision Oncology for Ovarian Cancer.- 15 Germline Findings from Genetic Testing for Breast Cancer.- 16 Hereditary Breast and Ovarian Cancer (HBOC) Database.- 17 Ethical Issues: Overview in Genomic analysis and Clinical Context.- 18 PARP Inhibitors-Mechanism of action.- 19 PARPi - Efficacy in Hereditary Breast Cancer.- 20 Efficacy of Poly ADP-Ribose Polymerase Inhibitors for Hereditary Ovarian Cancer.