Hereditary Breast and Ovarian Cancer

Molecular Mechanism and Clinical Practice

Häftad, Engelska, 2022

AvSeigo Nakamura,Daisuke Aoki,Yoshio Miki

1 579 kr

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This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease.

Produktinformation

Utgivningsdatum2022-10-22
Mått155 x 235 x 17 mm
Vikt565 g
FormatHäftad
SpråkEngelska
Antal sidor324
FörlagSpringer Verlag, Singapore
ISBN9789811645235

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Onkologisk kirurgi inom Medicin
Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin

1 History, Advancements, and Future Strategies.- 2 Molecular basis of BRCA1 and BRCA2 - Homologous recombination deficiency and tissue-specific carcinogenesis.- 3 Genetic Testing.- 4 Variants of uncertain significances in hereditary breast and ovarian cancer.- 5 Genetic counseling in Hereditary Breast and Ovarian Cancer.- 6 Hereditary Breast Cancer.- 7 Hereditary Ovarian Cancer.- 8 Risk-Based Breast Cancer Screening.- 9 Chemoprevention for Breast Cancer.- 10 Chemoprevention for Ovarian Cancer.- 11 Risk-Reducing Mastectomy (RRM).- 12 Risk-reducing salpingo-oophorectomy (RRSO).- 13 Panel Testing.- 14 Germline Findings through Precision Oncology for Ovarian Cancer.- 15 Germline Findings from Genetic Testing for Breast Cancer.- 16 Hereditary Breast and Ovarian Cancer (HBOC) Database.- 17 Ethical Issues: Overview in Genomic analysis and Clinical Context.- 18 PARP Inhibitors-Mechanism of action.- 19 PARPi - Efficacy in Hereditary Breast Cancer.- 20 Efficacy of Poly ADP-Ribose Polymerase Inhibitors for Hereditary Ovarian Cancer.