Professor René R.P. De Vries, Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands and President of the European Haemovigilance Network. Dr Jean Claude Faber, Director of the Blood Transfusion Service, Luxembourg Red Cross, Luxembourg.The editors are experts in the field of haemovigilance. Both are members of the Board of the International Haemovigilance Network (IHN) and of the International Society of Blood Transfusion (ISBT) Working Party on Haemovigilance.

• List of Contributors, viiiForeword, xiiPart 1 General Introduction1 Introduction, 3RenéR.P.deVries2 Hemovigilance: A Quality Tool for the Blood Transfusion Chain, 5RenéR.P.deVries3 Concepts and Models, 12René R.P. de Vries and Jean-Claude FaberPart 2 Hemovigilance of the Blood Transfusion Chain (Blood Establishment and Hospital)Section 2.1: Setting up a Hemovigilance System4 Setting Up or Consolidating a System for Donor Hemovigilance at the Level of a Blood Establishment, 21Johanna Wiersum-Osselton, Wim de Kort, Tanneke Marijt-van der Kreek, and Jeroen de Wit5 Preparation of Blood Components, 36Tomislav Vuk6 Establishment of Hemovigilance for the Testing, Storage, Distribution, Transport, and Issuing of Blood and Blood Components: The Example of Greece, 52Constantina Politis7 Medical Decision, Ordering, Administration of Component, and Monitoring of the Patient, 61Mickey B.C. Koh, Ramir Alcantara, Mark Grumbridge, and Ai Leen Ang Section 2.2: How the System Works8 Blood Donation: An Approach to Donor Vigilance, 77Peter Tomasulo, Madhav Erraguntla, and Hany Kamel9 Preparation of Blood Components, 99Erhard Seifried, Reinhard Henschler, Juergen Luhm, Thea Mueller-Kuller, Hans-Ulrich Pfeiffer, Walid Sireis, and Markus M. Mueller10 Testing, Issuing, and Transport of Blood Components, 113Constantina Politis11 Clinical Activities: Medical Decision-making, Sampling, Ordering Components, Administration, and Patient Monitoring, 126Clare TaylorPart 3 National or Regional Hemovigilance Systems12 The French Hemovigilance Network: From the Blood Scandal to Epidemiologic Surveillance of the Transfusion Chain, 147Philippe Renaudier13 The Japanese Hemovigilance System, 159Hitoshi Okazaki, Naoko Goto, Shun-ya Momose, Satoru Hino, and Kenji Tadokoro14 Setting up a National Hemovigilance System: SHOT, 168Hannah Cohen and Lorna M. Williamson15 The Dutch Hemovigilance System: Transfusion Reactions in Patients (TRIP), 180Martin R. Schipperus, Johanna Wiersum-Osselton, Pauline Y. Zijlker-Jansen, and Anita J.W. van Tilborgh-de Jong16 Regulatory, Public Health, and International Aspects of Hemovigilance in Canada, 191Peter R. Ganz and Jun Wu17 Setting up and Implementation of the National Hemovigilance System in Italy, 204Giuliano Grazzini and Simonetta Pupella18 The Australian Hemovigilance System, 209Erica M. Wood, Lisa J. Stevenson, Simon A. Brown, and Christopher J. Hogan19 Biovigilance in the United States, 220D. Michael Strong, Barbee Whitaker, Matthew J. Kuehnert, and Jerry A. Holmberg20 Arab Hemovigilance Network, 226Salwa Hindawi, Magdy Elekiaby, and Gamal GabraPart 4 Hemovigilance at the International Level21 Hemovigilance in the European Community, 235Jean-Claude Faber22 International collaboration, 253Paul F.W. Strengers23 Hemovigilance in Developing Countries, 260Jean-Claude FaberPart 5 Achievements24 Achievements Through Hemovigilance, 281Jean-Claude Faber and Fátima NascimentoPart 6 Developments25 Vigilance of Alternatives for Blood Components, 305Dafydd Thomas26 Surveillance of Clinical Effectiveness of Transfusion, 322Brian McClelland and Katherine Forrester27 Biovigilance, 326Jerry A. Holmberg, Matthew J. Kuehnert, and D. Michael StrongAppendicesAppendix A Glossary, 343Appendix B Proposed standard definitions for surveillance of non infectious adverse transfusion reactions, 351Appendix C Standard for surveillance of complications related to blood donation, 360Index, 369

“This is a thoroughly fascinating read and will make you eager to implement or enhance your current hemovigilance efforts. I recommend it.”  (Doody’s, 26 April 2013)