Hematopoietic Differentiation of Human Pluripotent Stem Cells

Tao Cheng is a professor and director of the State Key Laboratory of Experimental Hematology. He is also the vice president of Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China. He serves on the Editorial Boards of a number of well-known international journals, such as Leukemia, Experimental Hematology, and International Journal of Hematology. His research interests focus on hematology and stem cells. He has contributed enormously to our understanding of the cell cycle control of hematopoietic stem cells and has published more than 20 original research articles in top journals over the last 5 years.

• Generation of Hemangioblasts from Human Pluripotent Stem Cells.- Derivation of mature erythrocytes from human pluripotent stem cells by coculture with murine fetal stromal cells.- Derivation of megakaryocytes and platelets from human pluripotent stem cells.- Derivation of functionally mature eosinophils from human pluripotent stem cells.- Human Pluripotent Stem Cells As a Renewable Source of Natural Killer Cells.- Generation of T lineage cells from iPS cells and its application.- Reprogramming of Human Cord Blood CD34+ Cells into Induced MSCs.- CRISPR/Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells.- Humanized mouse models with functional human lymphoid and hematopoietic systems through human hematopoietic stem cell and human fetal thymic tissue transplantation.