Heavy Metal Toxicity and Neurodegeneration

Häftad, Engelska, 2025

Av Prasann Kumar, Neha Gogia, India) Kumar, Prasann, PhD (Assistant Professor, Department of Agronomy, School of Agricultural (ICAR-Accredited), Lovely Professional University, Punjab, USA) Gogia, Neha, MS, PhD (Post-Doctoral Associate, Yale University, Connecticut

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Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.

It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease.

Provides a comprehensive overview of how heavy metals interact with biological systems, particularly the nervous system
Explains the mechanisms through which metals contribute to neurodegenerative diseases
Highlights the public health implications of heavy metal exposure, including its impact on vulnerable populations such as children and older people

Produktinformation

Utgivningsdatum2025-08-14
Mått216 x 276 x 28 mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor592
FörlagElsevier Science
ISBN9780443365751

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Dr. Prasann Kumar, assistant professor cum research intensive faculty in theDepartment of Agronomy, School of Agricultural (ICAR-Accredited), LovelyProfessional University, Punjab, specializes in stress physiology, plant tissue culture,physiology of plant?microbe/pathogen interaction, and biodiversity management.Dr. Kumar has completed the International Agricultural Rural DevelopmentProgramme from Cornell University, Ithaca, New York, United States. He hasreceived a doctorate from Banaras Hindu University, Varanasi. He also hasauthored 40 books published by national and international publishers, which finda place in national as well as various Overseas Institutions’ libraries. He hasguided 19 MSc students for their thesis. Dr. Gogia is a Post-Doctoral Associate at Yale. Having completed her PhD degree at the University of Dayton, and Cornell University’s International Agriculture and Rural Development Program (IARD) she was awarded the Gerald L. Willis Award of Excellence for Outstanding Teaching in 2019. Her current work focuses on understanding cellular and molecular mechanisms underlying polyglutamine diseases, namely the identification and validation of genetic modifiers which can serve as potential therapeutic targets and can ameliorate the onset or progression of neurodegenerative diseases.

1. Biological pathways of heavy metal toxicityMridu Kulwant and Divya Patel2. Mechanisms of neurodegeneration induced by heavy metalsPrasann Kumar3. Lead toxicity and its impact on cognitive functionK. Jaisuriyan and Prasann Kumar4. Mercury poisoning: effects on the central nervous systemNeha Gogia and Prasann Kumar5. Arsenic exposure and neurotoxic effectsPriyanka Kharel and Prasann Kumar6. Cadmium and its role in neurodegenerative diseasesPrasann Kumar7. Chromium toxicity: neurological implicationsManisha Sharma and Prasann Kumar8. Interactions between heavy metals and neuroinflammatory processesDebjani Choudhury and Prasann Kumar9. Oxidative stress and heavy metal–induced neuronal damagePatan Ruksar and Prasann Kumar10. Genetic susceptibility to heavy metal toxicityPrasann Kumar11. The role of glutathione in heavy metal detoxificationPrasann Kumar12. Heavy metals and Alzheimer’s disease: a reviewBushra Bashir, Sapna Jarial, Shivalika Sood and Sukriti Vishwas13. Parkinson’s disease and heavy metal exposureAmit Raj and Prasann Kumar14. Multiple sclerosis: the impact of heavy metalsPrabhjot Singh Jassal and Tusha Yadav 15. Heavy metals and amyotrophic lateral sclerosisAmit Raj16. Neurodevelopmental disorders linked to heavy metal exposureMastu Patel17. Childhood exposure to heavy metals and long-term neurodevelopmental effectsMastu Patel and Prasann Kumar18. Environmental sources of heavy metals and their impacts on human healthMonika Sharma and Prasann Kumar19. Biomarkers of heavy metal–induced neurotoxicity: insights into mechanisms and disease impactKrupanshi Bharadava, Sanjay Kumar and Radhey Shyam Kaushal20. Diagnostic techniques for heavy metal induced neurotoxicityHirwe Onkar Ramchandra and Prasann Kumar21. Prevention and mitigation strategies for heavy metal exposureMakey Sri Chakra Naga Vardhan, Ashok S. Dambale, Prasann Kumar and Nilabja Banerjee22. Therapeutic approaches for heavy metal detoxificationPrasann Kumar23. Dietary interventions for reducing heavy metal toxicityPrasann Kumar and Shipa Rani Dey24. Pharmacological treatments for neurodegeneration due to heavy metalsPrasann Kumar25. The role of chelation therapy in heavy metal detoxificationVenkata Suneel Kumar Velugolu and Prasanna Kumar26. Impact of heavy metals on neuroplasticityPrasann Kumar and Shipa Rani Dey27. Heavy metal toxicity and psychiatric disordersDebjani Choudhury and Prasann Kumar28. Epidemiological studies on heavy metal exposure and neurodegenerationDebjani Choudhury and Prasann Kumar29. Regulatory standards and guidelines for heavy metal exposureB. Gopika and Prasann Kumar