Heat Shock Proteins in Human Diseases

Prof. Dr. Alexzander A. A. Asea is a highly innovative and accomplished world renowned clinical and basic research scientist and visionary executive leader who has exceptional experience spearheading clinical and basic science research, training, education, and commercialization initiatives within top ranked academic biomedical institutes. Prof. Dr. Asea’s initial findings studying the effects of Hsp72 on human monocytes lead to the proposal of a novel paradigm that Hsp72, previously known to be an intracellular molecular chaperones, can be found in the extracellular milieu where it has regulatory effects on immuno-competent cells - a term now called chaperokine. Prof. Asea has authored over 320 scientific publications including peer-reviewed articles, reviews, books, book chapters, editorials, and news headliners in a wide range of biomedical-related disciplines. Prof. Asea is the Editor-in-Chief of the widely successful book series Heat Shock Proteins (SpringerNature Publishing) and is an editorial board member of numerous scientific peer-reviewed journals. Prof. Dr. Asea is at the University of Toledo College of Medicine and Life Sciences in Toledo, USA.Dr. Punit Kaur is an expert in onco-proteogenomics, with extensive training and experience in quantitative mass spectrometry imaging, protein chemistry and biomarker discovery. Dr. Kaur’s main research focus is on the use of heat-induced nanotechnology in combination with radiotherapy and chemotherapy in the cancer stem cell therapy. Dr. Kaur has published more than 70 scientific articles, book chapters, and reviews, and currently serves as editorial board member for the European Journal of Cancer Prevention and the Journal of Proteomics and Bioinformatics. Dr. Kaur is the Associate Editor of the highly successful Heat Shock Proteins book series by Springer Nature Publishers. Currently, Dr. Kaur is at the University of Toledo College of Medicine and LifeSciences in Toledo, USA.

• Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and Cancer Immunotherapy.- Chaperonin Hsp60 and Cancer Therapies.- Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment.- Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics.- Multifaceted Roles of Heat Shock Factor 1 (HSF1) in Cancer.- Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer.- Heat Shock Proteins in Atrial Fibrillation.- Threading Microarrays into Novel Applications.- Regulation of Kaposi’s Sarcoma-associated Herpesvirus Biology by Host Molecular Chaperones.- Role of Heat Shock Factors in Diseases and Immunity.- Heat Shock Proteins and Pain.- Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway.- Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with diverse Cellular and Molecular Functions.- Roles of Heat Shock Proteins on Antigen Presentation.- Heat shock proteins mediate anastasis and plasticity of thermotolerant cells.