Head and Neck Cancers

Evidence-Based Treatment

Inbunden, Engelska, 2018

AvAthanassios Argiris,Robert L. Ferris,David I. Rosenthal

2 689 kr

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“Overall, this is an excellent book on an important topic in cancer that medical oncologists, pharmacologists, and nurses, as well as related healthcare professionals, may find very helpful.”Score: 100, 5 Stars, Doody’s Medical ReviewsHead and Neck Cancers: Evidence-Based Treatment presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with head and neck cancers, including oropharyngeal cancer, cancer of the oral cavity, laryngeal cancer, nasopharyngeal cancer, hypopharyngeal cancer, cancer of the sinuses and the skull base, salivary gland cancer, and neck lymphadenopathy.Section 1 of the book covers the most pertinent details on the epidemiology, biology, diagnosis and staging of the disease including topics such as the genomic landscape of squamous cell carcinoma of the head and neck and novel imaging modalities. Section 2 discusses the evidence-based treatment modalities for conventional and novel chemotherapy regimens, the evidence behind emerging radiation therapy techniques and the minimally invasive surgical advances changing the landscape of care. The chapters in Section 3 are dedicated to site-specific management, including management guidelines, tables with FDA-approved therapies and relevant ongoing clinical trials as well as instructive clinical cases with important discussion on outcomes and follow up care. Finally, Section 4 focuses on recurrent and metastatic disease and Section 5 provides the essentials on supportive care, including managing the elderly, managing patients suffering from dysphagia and oral complications, and must-know details of quality of life assessment and patient-reported outcomes.Emphasizing the practice-changing techniques and the latest evidence-based treatment advances including targeted therapies, immunotherapy, transoral robotic surgery, and radiation therapy precision, this comprehensive yet accessible textbook is indispensable for any clinical oncologist of each discipline wanting a balanced and evidence-based reference on managing patients with head and neck malignancies.Key Features:Includes didactic clinical cases for each type of head and neck cancerNumerous tables highlight FDA approved therapies and ongoing clinical trialsProvides evidence-based recommendations for treating head and neck cancers at each stage of the disease with conventional and novel treatment strategiesCovers strategies for managing acute and late complications to treatmentIncludes access to the fully-searchable downloadable e-book

Produktinformation

Utgivningsdatum2018-07-09
Mått178 x 254 x 38 mm
Vikt454 g
FormatInbunden
SpråkEngelska
Antal sidor550
FörlagSpringer Publishing Co Inc
ISBN9780826137777

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Athanassios Argiris, MD, FACP is Professor, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania.Robert L. Ferris, MD, PhD, FACS, UPMC Endowed Professor and Vice-Chair, Departments of Otolaryngology, of Immunology, and of Radiation Oncology and Chief, Division of Head and Neck Surgery, University of Pittsburgh Medical Center, Pittsburgh, PennsylvaniaDavid I. Rosenthal, MD, FACR, FASTRO, Professor of Radiation Oncology and Head and Neck Surgery, and Chief of the Head and Neck Radiation Oncology Service, University of Texas MD Anderson Cancer Center, Houston, Texas

ContentsContributorsPrefaceSECTION IEpidemiology, Biology, Diagnosis, and Staging1. Head and Neck Cancer EpidemiologyAngela L. Mazul, Erich M. Sturgis, Andrew F. Olshan, and Jose P. Zevallos2. Pathology of HNSCCMichelle D. Williams and Adel K. El-Naggar3. The Genomic Landscape of HNSCCSteffen Wagner, Jens P. Klussmann, and Ruud H. Brakenhoff4. HPV-Related Head and Neck Cancer BiologyFarhoud Faraji and Carole Fakhry5. Imaging of Head and Neck CancersRathan M. SubramaniamSECTION IIEstablished and Emerging Treatment Modalities6. Advances in Radiation Therapy Techniques for HNSCC: Image-Guided RT Stereotactic, IMRT-VMAT, MRI-Linac and SimulationJussi Sillanpaa, C. Jillian Tsai, and Nancy Y. Lee7. Proton TherapyPierre Blanchard, G. Brandon Gunn, and Steven J. Frank8. Transoral Robotic Surgery: Advances and ApplicationsMeghan T. Turner, F. Christopher Holsinger, and Robert L. Ferris9. Induction Chemotherapy: Current and Emerging Role in HNSCCGlenn J. Hanna and Robert I. Haddad10. Immunotherapy for HNSCC: Rationale and Clinical ApplicationsJennifer Moy, Jennifer M. Johnson, Jessica Moskovitz, Robert L. Ferris, and Athanassios Argiris11. Targeting the Human Epidermal Receptor Family in HNSCCEmmanuel Seront, Sandra Schmitz, and Jean-Pascal Machiels12. Therapies Targeting VEGF/Angiogenesis and Other Novel Targets and Therapies in HNSCCSophie Stock-Martineau, Yanqun Dong, Denis Soulières, and Thomas J. GallowaySECTION IIISite-Specific Management13. Oropharyngeal Cancer: HPV-Positive DiseaseChristien A. Kluwe, Anthony J. Cmelak, and Barbara A. Burtness14. Non–HPV-Associated Oropharyngeal CancerMeghan T. Turner, Anirudh Saraswathula, and F. Christopher Holsinger15. Oral Cavity Cancer: Surgical Approaches and Postoperative TreatmentAntoine Eskander, Jacques Bernier, Lisa Licitra, Paolo Bossi, and Theodoros N. Teknos16. Nasopharyngeal CancerWai Tong Ng, Oscar S. H. Chan, Henry C. K. Sze, Ka On Lam, and Anne W. M. Lee17. Hypopharyngeal Cancer: A Multidisciplinary ApproachMoran Amit, Loren K. Mell, Cristina P. Rodriguez, and Neil D. Gross18. Laryngeal Cancer: Organ Preservation StrategiesArlene A. Forastiere, Jae Lee, Steven B. Chinn, Karim Boudadi, Avraham Eisbruch, Randal S. Weber19. Malignancies of the Paranasal Sinuses and Skull BaseHeather A. Osborn, Jong Chul Park, Nabil F. Saba, Pierre Blanchard, and Derrick T. Lin20. Evaluation and Treatment of Metastatic Lymphadenopathy From an Unknown PrimaryShirin Attarian, Richard Blake Ross, Shlomo A. Koyfman, and Missak Haigentz, Jr.21. Salivary Gland MalignanciesCristina P. Rodriguez, Jessica L. Geiger, Jon Mallen-St. Clair, Patrick K. Ha, Sue S. Yom, Adam S. Garden, and David J. AdelsteinSECTION IVRecurrent or Metastatic Disease22. Locally Recurrent HNSCC: Salvage Surgery, ReirradiationAntoine Eskander, Sharon A. Spencer, Corey J. Langer, Takashi Maruo, Ryuichi Hayashi, Sadamoto Zenda, and James W. Rocco23. Recurrent or Metastatic HNSCC: Systemic TherapyTomohiro Enokida, Susumu Okano, and Makoto TaharaSECTION VSupportive Care and Special Patient Groups24. Oral ComplicationsRajesh V. Lalla and Douglas E. Peterson25. Dysphagia in Patients With Head and Neck CancerKatherine A. Hutcheson and Jan S. Lewin26. Quality of Life Assessment and Patient-Reported Outcomes in Head and Neck CancerMinh Tam Truong and Lisa Ann Kachnic27. Management of Head and Neck Cancers in the ElderlyJessica L. Geiger and Julie E. BaumanIndex

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