Handbook of Pharmacogenomics and Stratified Medicine

Dr. Sandosh Padmanabhan MD, PhD, FRCP, FAHA, FBHS, FBPhS is a Professor and Physician at the Institute of Cardiovascular and Medical Sciences, University of Glasgow. Dr. Padmanabhan completed his MBBS and MD at JIPMER, Pondicherry, India and was awarded the Gold Medal for MD General Medicine in 1995. His PhD thesis (1999-2003) on G-protein signaling in hypertension was awarded the Bellahouston Medal by the University of Glasgow in 2004, and he received the Austin Doyle Award from the International Society of Hypertension in 2004. Dr. Padmanabhan’s pharmacogenetic genome-wide linkage study led to a BHF Intermediate Fellowship (2006-2009), and he also led a genome wide association analysis of hypertension between 2008 and 2010, resulting in the discovery of a new gene and pathway for hypertension. Dr. Padmanabhan was a visiting fellow to the Broad Institute of Harvard and MIT (2010-2012). Currently, he is a Fellow of the Royal College of Physicians, the British Hypertension Society, and the American Heart Association. His active research areas span the genetics of cardiovascular traits, pharmacogenomics and stratified medicine, and hypertension epidemiology.

• I. IntroductionII. Basic geneticsIII. Experimental and discovery platformsIV. Statistics, bioinformatics, and databasesV. Clinical trialsVI. Fundamental pharmacogenomicsVII. Applications in therapeuticsVIII. Implementation and regulatoryIX. Global perspective

"…a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time." --Anticancer Research, January 2015"This is an extremely useful resource for clinicians, scientists, or any individuals interested in an excellent review of the rapidly advancing field of pharmacogenomics and its increasing relevance for clinical practice. - Rating: 5 Stars" --Doody's.com, Oct 2014