Handbook of Gastrointestinal Cancers is a practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower gastrointestinal tract. Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care. The handbook focuses on treatment strategies and approaches to cancerous gastrointestinal tumors that are transforming the recent oncological landscape, including expert-given guidance on methods such as neoadjuvant and adjuvant chemotherapy, surgical transplant, radiation therapy, molecular diagnostic testing leading to molecularly targeted therapy, and immunotherapy.With so many advances in the current field, it is increasingly difficult for early-career practitioners to grasp the entirety of practices and for seasoned oncologists to keep up with newly approved therapies, side effects to treatments, and special clinical management considerations, but this handbook addresses it all. Organized by major gastrointestinal disease sites and featuring “How I Treat” case vignettes from world experts for common and uncommon management considerations, the handbook brings an experience-based perspective to these tough-to-treat areas. The treatment strategies and applications set forth in the chapters are pertinent to situations and decision-making encountered in practice. Handbook of Gastrointestinal Cancers is a valuable resource for medical oncologists, radiation oncologists, and surgeons treating and managing gastrointestinal cancers as well as trainees in medical, radiation, and surgical oncology programs needing an accessible point of care resource.KEY FEATURES:Provides treatment plans and recommendations for each stage of a range of gastrointestinal cancers, including colorectal, pancreatic, and hepatocellular cancers plus moreIncludes “How I Treat” patient vignettes told from the physician’s point of view within each clinical chapterOutlines special considerations for the elderly and for survivors of gastrointestinal cancersHighlights important clinical guidance on nutritional and palliative concerns commonly seen in patients with gastrointestinal cancers
Tanios Bekaii-Saab, MD, FACP, is Professor of Medicine, Senior Associate Consultant of Hematology and Oncology, and Co-Leader of the Gastrointestinal Cancer Program at the Mayo Clinic Cancer Center in Scottsdale, Arizona.
I- Colorectal Cancer:1. Epidemiology of Colorectal Cancer: Amit Surya Narayan, Christina Wu, and Walid L. Shaib2. Diagnosis and Staging of Colorectal Cancer: Amit Surya Narayan, Christina Wu, and Walid L. Shaib3. Molecular Diagnostic Guidelines for Colorectal Cancer: Christine Wu, Walid L. Shaib, and Ibrahim Halil Sahin4. How I Treat Early Stage Colon Cancer Through Surgery: Mark W. Arnold5. How I Treat Early Stage Colon Cancer with Adjuvant Therapy: Who and How Long?: Francesca Battaglin and Heinz-Josef Lenz6. How I Treat Early Stage Rectal Cancer with Neoadjuvant Therapy with Radiation: Nikhil Sebastian and Terence Williams7. How I Treat Early Stage Rectal Cancer Through Surgery: Nitin Mishra8. How I Treat Early Stage Rectal Cancer with Adjuvant Therapy: Gabriel A. Brooks9. How I Treat Oligometastatic Colorectal Cancer Through Surgery: Rory L. Smoot and David M. Nagorney10. How I Treat Oligometastatic Colorectal Cancer with Neoadjuvant Chemotherapy: Marwan Fakih11. How I Treat Oligometastatic Colorectal Cancer Through Local Non-Surgical Approaches: Sadeer Alzubaidi, Alex Wallace, and Rahmi Oklu12. How I Treat Oligometastatic Colorectal Cancer with Adjuvant Chemotherapy: Andrea Cercek and Gustavo dos Santos Fernandes13. How I Treat Oligometastatic Colorectal Cancer with Debulking/HIPEC in Limited Peritoneal Disease: Ed Levine14. How I Treat Metastatic Colorectal Cancer with Chemotherapy and Choice of Biologics: Kristen K. Ciombor and Satya Das15. How I Treat Metastatic Colorectal Cancer with Maintenance Therapies: Sakti Chakrabarti and Joleen M. Hubbard16. How I Treat Metastatic Colorectal Cancer with Emerging Therapeutic Strategies: Niharika B. Mettu and John H. Strickler17. How I Treat Metastatic Colorectal Cancer with Immunotherapy: Michael Lam and Shubham PantII- Pancreatic Cancer:18. Epidemiology of Pancreatic Cancer: Mehmet Akce, Alexandra G. Lopez-Aguiar, David A. Kooby, Field F. Willingham, Gregory B. Lesinski, and Shishir K. Maithel19. Biological Basis for Pancreatic Cancer: Brandon Ware, Mehmet Akce, Alexandra G. Lopez-Aguiar, David A. Kooby, Field F. Willingham, Shishir K. Maithel, Gregory B. Lesinski20. Diagnosis and Staging of Pancreatic Cancer: Ramzi Mulki, Parit Mekaroonkamol, Alexandra G. Lopez-Aguiar, Gregory B. Lesinski, David A. Kooby, Mekmet Akce, Shishir K. Maithel, and Field F. Willingham21. The Role and Timing of Surgery in Pancreatic Cancer: Mark Truty22. How I Treat Resectable PancreaticCancer with Adjuvant Therapy: Philip A. Philip and Mandana Kamgar23. How I Treat Resectable Pancreatic Cancer with Neoadjuvant Therapy: Davendra P. S. Sohal24. How I Treat Borderline Resectable and Locally Advanced Pancreatic Cancer: Hao Xie, Tanios Bekaii-Saab, and Wen Wee Ma25. How I Treat Metastatic Pancreatic Cancer with Chemotherapy: Benjamin A. Krantz and Eileen M. O’Reilly26. How I Treat Metastatic Pancreatic Cancer with Emerging Targets: Benjamin A. Krantz and Eileen M. O’ReillyIII- Hepatocellular Cancer:27. Epidemiology of Hepatocellular Cancer: Safi Shahda and Bert O’Neil28. Diagnosis and Staging of Hepatocellular Cancer: Safi Shahda and Bert O’Neil29. Cellular and Molecular Pathology of Hepatocellular Cancer: Safi Shahda and Bert O’Neil30. How I Treat Early-Stage Hepatocellular Cancer Through Transplant: Emmanouil Girogakis and Amit K. Mathur31. How I Treat Early-Stage Hepatocellular Cancer Through Surgery: Rachel M. Lee and Kenneth Cardona32. How I Treat Early-Stage Hepatocellular Cancer with Local Non-Surgical Approaches: Junaid Raja and Hyun S. Kim33. How I Treat Early-Stage Hepatocellular Cancer with Local Non-Surgical Approaches: Jonathan B. Ashman34. How I Treat Advanced Hepatocellular Cancer with Multikinase Inhibitors and Other Targeted Therapies: Kabir Mody and Ghassan K. Abou-Alfa35. How I Treat Advanced Hepatocellular Cancer with Immunotherapy: Olatunji B. Alese and Katerina ZakkaIV- Gastric and Esophageal Cancer:36. Epidemiology of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn37. Diagnosis and Staging of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn38. Molecular Diagnostic Guidelines of Gastric and Esophageal Cancer: Mohamad Bassam Sonbol and Daniel H. Ahn39. How I Treat Early Stage Gastric and Esophageal Cancer with Neoadjuvant Therapy: William A. Stokes and Karyn A. Goodman40. How I Treat Early Stage Gastric and Esophageal Cancer with Surgery: Sajid A. Khan, Vadim Kurbatov, and Mitchell C. Posner41. How I Treat Metastatic Gastric and Esophageal Cancer with Chemotherapy and Choice of Biologics: Mehmet Akce42. How I Treat Metastatic Gastric and Esophageal Cancer with Immunotherapy: Curtis R. Chong and Yelena Y. JanjigianV- Rare Gastrointestinal Cancers:43. Molecular Diagnostic Guidelines of Cancers of the Bile Ducts and Gallbladder: Talal Hilal and Mitesh J. Borad44. Surgery for Early-Stage Cancers of the Bile Ducts and Gallbladder: Jordan Cloyd, Charlie Kimbrough, and Timothy M. Pawlik45. Adjuvant Therapy for Early-Stage Cancers of the Bile Ducts and Gallbladder: Flavio G. Rocha46. Chemotherapy for Advanced Cancers of the Bile Ducts and Gallbladder: Jonathan Whisenant47. Emerging Therapies for Advanced Cancers of the Bile Ducts and Gallbladder: Madappa Kundranda and Milind Javle48. Neuroendocrine Tumors: Jonathan Strosberg49. Early-Stage Anal Cancer: Clayton A. Smith, Nitesh Rana, and Lisa A. Kachnic50. Metastatic Anal Cancer: Saivaishnavi Kamatham, Faisal Shahjehan, and Pashtoon M. Kasi51. Gastrointestinal Stromal Tumors (GIST): Kantha Ratnam Kolla and Mahesh SeetharamVI- Special Clinical Considerations for Gastrointestinal Cancer Patients:52. Nutritional Needs for Gastrointestinal Cancer Patients: Tiffany Barrett53. Palliative Carefor Gastrointestinal Cancer Patients: Angelia Curseen54. Care for Elderly Gastrointestinal Cancer Patients: Grant R. Williams and Hanna K. Sanoff55. Survivorship Care for Gastrointestinal Cancer Patients: Nataliya V. Uboha, Mary Mulkerin, Stephanie L. Fricke, and Noelle K. LoConte