Hand transplantation

• Historical Remarks.- Cosmas and Damian Revisited.- Hand Transplantation as an Evolution of Microsurgery: A Logical Step Towards Better Reconstructive Options.- Experimental Limb Transplantation.- Hind-Limb Transplantation in the Rat: Surgical Technique, Anaesthesia and Early Postoperative Management.- Indefinite Survival and Functional Recovery of Limb Allografts in Rodents.- Induction of High-Level Chimerism in Composite Tissue Transplants.- Simultaneous Vascularised Bone Marrow Transplantation to Promote Acceptance of Limb Allografts.- Experimental Approaches to Composite Tissue Allograft Transplants.- A Review of Current Strategies to Achieve Tolerance in Animal Models.- The History of Experimental Hand Transplantation in Primates.- Hand Transplantation in Monkeys: Technical Details and Immunological Aspects.- Ethics and Medico-Legal Implications.- Ethical Aspects of Non-Life-Saving Allografts with Special Regard to the Hand.- Ethical Issues of Organ Transplantation in Non-Life-Saving Situations.- Informed Consent, Medico-Legal Implications, Public and Private Insurance Issues and Quantification of Disability in Hand Transplantation.- Living with Two Different Fingerprints: Legal Implications and Identification Issues.- Organization of Hand Transplantation.- Selection of Candidates and Waiting List, Dealing with the Media and the Public, Setting Up a Pilot Study, Clinical Trial Organization, Staff Requisites for Hand Transplantation: The Lyon Experience.- Selection of Candidates and Waiting List, Dealing with the Media and the Public, Setting Up a Pilot Study, Clinical Trial Organization, Staff Requisites for Hand Transplantation:The Milan Experience.- Selection of Candidates and Waiting List, Dealing with the Media and the Public, Setting Up a Pilot Study, ClinicalTrial Organisation, Staff Requisites for Hand Transplantation: The Innsbruck Experience.- Selection of Candidates and Waiting List, Dealing with the Media and the Public, Setting Up a Pilot Study, Clinical Trial Organization, Staff Requisites for Hand Transplantation: The Brussels Experience.- Patient Management and Follow-up.- Surgical Technique of Hand Transplantation.- Instruments, Sutures and Needles for Hand Transplantation.- Anaesthetic Management.- Harvesting the Hand.- Preparing the Recipient.- Technical and Surgical Details of Hand Transplantation.- Hand Replantation and Transplantation: More Differences than Similarities.- Immunology of Hand Transplantation.- Current Concepts.- Immunosuppressive Therapy.- Induction and Maintenance Therapy.- Side-Effects and Potential Complications.- CMV Infection and Reactivation.- Specific T-Cell Response to HCMV Infection.- Ocular Complications after Hand Transplantation.- Limb Rejection and Monitoring.- Skin Rejection in Human Hand Allografts: Histological Findings and Grading System.- Pharmacological Treatment of Rejection.- Monitoring Rejection with a Distant Sentinel Skin Graft.- Functional Recovery of Transplanted Hands.- Bone Healing in Hand Transplantation.- Return of Sensibility and Motor Recovery of Extrinsic and Intrinsic Muscles.- From Silent Neuroma to Reactivation of Axonal Growth: How a Peripheral Nerve can Start to Regenerate into a Transplanted Hand?.- Modified Visual Feedback in Rehabilitation.- Analysis of Motor Unit Reinnervation in Muscles of the Transplanted Hand.- Role of the Sympathetic Nervous System on Arterial Distensibility.- An Instrumental Kit for a Comprehensive Assessment of Functional Recovery.- Human Brain Plasticity after Bilateral Hand Allograft.- The Sensor Glove in Preoperative Conditioning and Postoperative Rehabilitation.- A Comprehensive Functional Score System in Hand Transplantation.- Quality of Life in Hand Transplant Patients.- Psychological Issues in Hand Transplantation.- Psychological Evaluation and Patient’s Profile.- Hand Transplant and Body Image.- Psychological Effects of Hand Transplantation.- Other Composite Tissue Transplant.- Allogeneic Vascularised Knee Transplantation.- Laryngeal Transplantation.- Uterus Transplantation.- Abdominal Wall Transplantation: A Review of the Literature.- First Human Face Allograft: Report at 4 months.- Lower-Extremity Hindquarter Transplantation in Conjoined Twins.- Future Directions.- Limb Transplantation in Congenital Deformities.- Mechanisms Involved in the Induction of Tolerance in Allogeneic Hand Transplantation: A Proposal.- Induction of Tolerance in Allotransplantation.- The International Registry on Hand and Composite Tissue Transplantation (IRHCTT).- The International Registry on Hand and Composite Tissue Transplantation (IRHCTT).- An Extensive Bibliography on Hand Transplantation.- An Extensive Bibliography on Hand Transplantation.

From the reviews: "Hand Transplantation is organized into 14 sections ... . Each chapter is replete with excellent color plates, illustrations, radiographic images, tables, and figures that fully complement the text. The book includes a bibliography of hand transplantation that is contemporary and comprehensive Lanzetta and Dubernard should be complimented on this book, which provides stimulating and interesting reading about a groundbreaking field that is at the frontier of reconstructive surgery." (Vijay S. Gorantla and W. P. Andrew Lee, New England Journal of Medicine,Vol. 358 (1), January, 2008)