Guide to Numerical Modelling in Systems Biology

Peter Deuflhard, founder of ZIB and co-founder of MATHEON in Berlin, has written successful books in numerical analysis and scientific computing (three of them with Springer). Susanna Röblitz is Head of the research group Computational Systems Biology at ZIB and professor for Applied Mathematics and Bioinformatics at FU Berlin.

• Preface.- Outline.- ODE Models for Systems Biological Networks.- Numerical Simulation of ODE Models.- Parameter Identification in ODE Models.- Appendix.- Software.- Index.

"This book is structured in three chapters covering the ODE modeling for the identification and characterization of biological networks, the handling of numerical simulations for the proposed ODE models and the corresponding parameters identification, respectively. ... included a list of numerical algorithms and software packages that facilitate the understanding of the ODE-related problems. ... written in an accessible manner, with plenty of examples, making it a valuable addition to the series of textbooks in computational science and engineering." (Irina Ioana Mohorianu, zbMATH, Vol. 1325.92001, 2016) "It focuses almost solely on the mundane mathematical topic of ordinary differential equations (ODEs) and their parameter estimation ... . the prime readership for this volume is to be found more amongst advanced researchers in systems biology trying to find reasons for unstable results of some ODE simulation or identification packages." (L.-F. Pau, Computing Reviews, November, 2015)