Good Research Practice in Non-Clinical Pharmacology and Biomedicine

Inbunden, Engelska, 2020

Av Anton Bespalov, Martin C. Michel, Thomas Steckler

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This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Produktinformation

Utgivningsdatum2020-02-21
Mått155 x 235 x 29 mm
Vikt816 g
FormatInbunden
SpråkEngelska
SerieHandbook of Experimental Pharmacology
Antal sidor423
FörlagSpringer Nature Switzerland AG
ISBN9783030336554

Tillhör följande kategorier

Onkologi inom Medicin
Hjärt- och kärlsjukdomar inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Farmakologi inom Medicin

1. Quality in Non-GxP Research Environment.- 2. Guidelines & Initiatives for Good Research Practice.- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices.- 4. General Principles of Preclinical Study Design.- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research.- 6. Blinding and Randomization.- 7. Out of control? Managing baseline variability in experimental studies with control groups.- 8. Quality of Research Tools.- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies.- 10. Building robustness intro translational research.- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research.- 12. Minimum Information in In Vivo Research.- 13. A reckless guide to P-values: Local evidence, global errors.- 14. Electronic Lab Notebooks and Experimental Design Assistants.- 15. Data storage.- 16. Design of meta-analysis studies.- 17. Publishers’ responsibilities in promoting data quality and reproducibility.- 18. Quality governance in biomedical research.- 19. Good Research Practice – Lessons from Animal Care & Use.- 20. Research collaborations and quality in research: foes or friends?.- 21. Costs of implementing quality in research practice.