Gold Nanoparticle Therapeutics in Alzheimer's Disease

Arun Kumar Singh completed his Master of Pharmacy (M. Pharm) in Pharmaceutics from Galgotias University, Greater Noida, India. He is currently an Assistant Professor in the Department of Pharmacy at Vivekanand Global University, where he is actively engaged in teaching and research.His research interests encompass various emerging and interdisciplinary fields, including nano-formulation, blockchain technology, the Internet of Things (IoT), machine learning, cancer biology, artificial intelligence, big data analytics, and neuroscience. Demonstrating a strong commitment to academic excellence, Mr. Singh has made significant contributions to the scientific community.Dr. Mahesh Narayan is a Full Professor in the Department of Chemistry and Biochemistry at the University of Texas at El Paso in the United States. Dr Narayan obtained his B.Sc. in Physics from Bombay University [1991], Ph.D. in Biophysics from The Ohio State University [1997], and pursued postdoctoral studies at Cornell University, USA [1997-2000] and was a Sr. Res. Assoc. at Cornell University [2002-05], USA. He has authored and co-authored several articles and book chapters in the fields of free radical biology, protein-structure function, oxidative folding, and protein misfolding, halogen bonding and in silico drug design, agricultural impact of nanomaterials, and chemical education. His work has been recognized by invitations to speak at over 15 international forums, as well as coverage in a variety of media outlets. The overall goal of his research program is to develop a better understanding of the intracellular processes and events that underlying the pathogenesis of neurodegenerative disorders. He is particularly interested in the effects of xenobiotics on amyloid proteins. This is since the majority of neurodegenerative disorders are sporadic, and environmental agents such as pesticides and certain drugs of abuse are risk factors for such neuropathies. Dr. Ashutosh Pareek, Associate Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.

• 1. Introduction to Alzheimer’s Disease: Current Challenges and Opportunities2. Fundamentals of Gold Nanoparticles: Properties, Synthesis, and Functionalization3. Pathophysiological Mechanisms of Alzheimer’s Disease and Gold Nanoparticles Intervention4. Diagnostic Applications of Gold Nanoparticles in Alzheimer’s Disease5. Gold Nanoparticles for Drug Delivery in Alzheimer’s Disease6. Glyco-Gold Nanoparticles: Advances in Targeted Therapy for Alzheimer’s Disease7. Nucleic Acid-Based Therapies Delivered by Gold Nanoparticles8. Immunotherapeutic Approaches Using Gold Nanoparticles in Alzheimer’s Disease9. Regenerative Medicine: Gold Nanoparticles in Neural Tissue Repair10. Clinical Translation of Gold Nanoparticle Therapies: Challenges and Opportunities11. Ethical Considerations and Regulatory Aspects of Gold Nanoparticle Use12. Future Perspectives and Emerging Trends in Gold Nanoparticle Research for Alzheimer’s Disease