Gold Nanoparticle Therapeutics in Alzheimer's Disease

Arun Kumar Singh is an Assistant Professor in the Department of Pharmacy at University School of Pharmaceutical Sciences, Rayat Bahra University V.P.O. Sahauran , India. He completed his M.Pharm in Pharmaceutics from Galgotias University, Greater Noida. His research interests include nano-formulation, blockchain, IoT, machine learning, artificial intelligence, big data analytics, cancer biology, and neuroscience. He has contributed to academic books and book chapters and has published review articles in the areas of pharmaceutical sciences and healthcare technology. His work focuses on interdisciplinary approaches integrating pharmaceutical research with emerging digital and computational technologies. Dr. Mahesh Narayan is a Professor in the Department of Chemistry and Biochemistry at the University of Texas at El Paso (USA). He earned a B.Sc. in Physics from Bombay University (1991) and a Ph.D. in Biophysics from The Ohio State University (1997). He completed postdoctoral studies at Cornell University (1997–2000) and later served as a Senior Research Associate there (2002–2005). Dr. Narayan has authored and co-authored articles and book chapters in free radical biology, protein structure-function relationships, oxidative folding, protein misfolding, halogen bonding, in silico drug design, the agricultural impact of nanomaterials, and chemical education. His work has been recognized by invitations to speak at over 15 international forums and by coverage in various media outlets. His research focuses on intracellular mechanisms in neurodegenerative disorders, particularly the effects of xenobiotics on amyloid proteins. Dr. Ashutosh Pareek, Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.

• 1. Introduction to Alzheimer’s Disease: Current Challenges and Opportunities2. Fundamentals of Gold Nanoparticles: Properties, Synthesis, and Functionalization3. Pathophysiological Mechanisms of Alzheimer’s Disease and Gold Nanoparticles Intervention4. Diagnostic Applications of Gold Nanoparticles in Alzheimer’s Disease5. Gold Nanoparticles for Drug Delivery in Alzheimer’s Disease6. Glyco-Gold Nanoparticles: Advances in Targeted Therapy for Alzheimer’s Disease7. Nucleic Acid-Based Therapies Delivered by Gold Nanoparticles8. Immunotherapeutic Approaches Using Gold Nanoparticles in Alzheimer’s Disease9. Regenerative Medicine: Gold Nanoparticles in Neural Tissue Repair10. Clinical Translation of Gold Nanoparticle Therapies: Challenges and Opportunities11. Ethical Considerations and Regulatory Aspects of Gold Nanoparticle Use12. Future Perspectives and Emerging Trends in Gold Nanoparticle Research for Alzheimer’s Disease