Glaucoma

Methods and Protocols

Häftad, Engelska, 2018

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Given that the retinal ganglion cells damaged and destroyed by glaucoma do not regenerate after lowering the intraocular pressure, new therapeutic approaches that protect ganglion cells directly is a vital research goal that this volume’s contents aim to aid scientists in developing.

Produktinformation

Utgivningsdatum2018-08-30
Mått178 x 254 x 20 mm
Vikt663 g
FormatHäftad
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor337
FörlagHumana Press Inc.
ISBN9781493984763

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Medicinsk utrustning och medicinska tekniker inom Medicin

Use of Animal Models and Techniques in Glaucoma Research: Introduction.- Hypertonic Saline Injection Model of Experimental Glaucoma in Rats.- The Microbead Occlusion Model of Ocular Hypertension in Mice.- Ocular Hypertension/Glaucoma in Minipigs: Episcleral Veins Cauterization and Microbead Occlusion Methods.- Non-Invasive Intraocular Pressure Measurement in Animals Models of Glaucoma.- High Throughput Binocular Pattern Electroretinograms in the Mouse.- Visual Evoked Potentials in Glaucoma and Alzheimer’s Disease.- Investigation of the Functional Retinal Output Using Microelectrode Arrays.- Quantitative Proteomic Analysis of Human Aqueous Humor Using iTRAQ 4plex Labeling.- Sphingolipid Analysis of Aqueous Humor.- Assessment of Aqueous Humor Dynamics in the Rodent by Constant Flow Infusion.- Methods for Analyzing Endoplasmic Reticulum Stress in the Trabecular Meshwork of Glaucoma Models.- Quantification of Scleral Biomechanics and Collagen Fiber Alignment.- Biolistic Labeling of RetinalGanglion Cells.- Anterograde Tract Tracing for Assaying Axonopathy and Transport Deficits in Glaucoma.- In Vitro and In Vivo Methods for Studying Retinal Ganglion Cell Survival and Optic Nerve Regeneration.- 3D Histomorphometric Reconstruction and Quantification of the Optic Nerve Head Connective Tissues.- Visualizing Astrocytes of the Optic Nerve.- Investigation of MicroRNA Expression in Experimental Glaucoma.- Utilizing RNA-Seq to Identify Differentially Expressed Genes in Glaucoma Model Tissues, Such as the Rodent Optic Nerve Head.- Single-Cell Dissociation and Characterization in the Murine Retina and Optic Nerve.