GHRH, GH, and IGF-I

Basic and Clinical Advances

Inbunden, Engelska, 1995

AvM. R. Blackman,Serono Symposia USA,Marc R. Blackman,S. Mitchell Harman,Jesse Roth,Jay R. Shapiro

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This volume contains the proceedings of the Symposium on GHRH, GH, and IGF-1: Basic and Clinical Advances, held December 9 - 12, 1993 in San Diego, California. Written and edited by eminent international experts, the papers herein cover: an overview of the physiology of GHRH-Somatostatin-GH-IGF-1 axis; the effects of recombinant human GH and/or IGF-1 in catabolic illness; contemporary issues in growth and development; the effects of rhGH and IGF-1 on intermediary and bone metabolism; and the use of GHRH, rhGH, and rhIGF-1 in aging.

Produktinformation

Utgivningsdatum1995-06-02
Mått155 x 235 x 24 mm
Vikt688 g
FormatInbunden
SpråkEngelska
SerieSerono Symposia USA
Antal sidor319
Upplaga1995
FörlagSpringer-Verlag New York Inc.
ISBN9780387944043

Tillhör följande kategorier

Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik
Endokrinologi inom Medicin
Fysiologi inom Medicin

I. Overview of Physiology of the GHRH-Somatostatin-GH-IGF-I Axis.- 1. Physiology of the Growth Hormone Releasing Hormone-Somatostatin-Growth Hormone-Insulin-Like Growth Factor I Axis.- 2. Role of Somatostatin in the Regulation of Growth Hormone Secretion.- 3. Growth Hormone Releasing Hormone and Growth Hormone Releasing Peptides.- 4. GH Binding Protein, GH Receptors, and Domains Involved in Signal Transduction.- 5. Insulin-Like Growth Factors During Development.- II. Effects of Recombinant Human GH and/or IGF-I in Catabolic Illness.- 6. Anabolic Effects of Recombinant Human Growth Hormone and Insulin-Like Growth Factor I in Human Disease.- 7. Growth Hormone in Children with Chronic Renal Disease: Some Metabolic Considerations.- 8. Growth Hormone: The Visible Difference in Burn Care.- 9. Effects of Recombinant Human Growth Hormone on Body Composition and Metabolism in HIV-Associated Wasting.- 10. Administration of Growth Hormone as an Adjunct to Nutritional Support in Critical Illness.- 11. Strategies for the Use of Recombinant Human Growth Hormone and Insulin-Like Growth Factor I in Amyotrophic Lateral Sclerosis.- III. Contemporary Issues in Growth and Development.- 12. Contemporary Issues in Growth and Development: An Overview.- 13. Use of Recombinant IGF-I in Syndromes of GH Insensitivity.- 14. Use of Growth Hormone in Non-Growth-Hormone-Deficient Children: Physiologic, Pharmacologic, and Ethical Issues.- 15. Growth Hormone Treatment of Nonelderly Adults with GH Deficiency.- IV. Effects of rhGH and IGF-I on Intermediary and Bone Metabolism.- 16. Overview of Growth Hormone and IGF-I Effects on Intermediary Metabolism and Bone.- 17. Effects of rhGH on Glucose, Lipid, and Amino Acid Metabolism.- 18. Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus.- 19. Modulation of Responses to GH and IGF-I by Nutritional Variables.- 20. Growth Hormone Effects on the Adult Skeleton.- 21. Insulin-Like Growth Factors and Skeletal Remodeling.- V. Use of GHRH, rhGH, and rhIGF-I in Aging.- 22. Growth Hormone and Aging: A Brief Review.- 23. Potential Benefits and Risks in Treating the Hyposomatomedinemia and Hypogonadism of Elderly Men.- 24. Effects of Growth Hormone Releasing Hormone Administration in Healthy Aging Men.- 25. Effects of Recombinant Human Insulin-Like Growth Factor I in Aging.- 26. Growth Hormone and Immune Function in the Elderly.- 27. Treatment with Growth Hormone: Focus on Specificity with a View to the Future.- Author Index.