Genomics in Biosecurity

Dr. Manousos E. Kambouris serves as a Scientific Advisor for the Golden Helix Foundation, Craven House, London, UK, an international non-profit research organization aiming to advance research and education in the area of genomic and personalized medicine and as a Post Doc Researcher in the Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras. Dr. Kambouris has long participated in different aspects and applications of microbiology, human genomics, biosecurity and cancer research. In his own work, he pursues an integrative approach to microbiomics, employing various -omics-driven approaches and realizing their application in human health, selective and personalized medicine, and panbiosurveillance among other areas. He has published widely in such peer-reviewed journals as OMICS-JIB, Hemoglobin, Medical Mycology, FEMS Immunology & Medical Microbiology, Public Health Genomics, and Future Microbiology.

• Part I. The Spontaneous Risk: Microbes and Bugs1. Exploring the concepts: Biosecurity, biodefense and biovigilance2. The concept of humanome and the microbiomic dimension3. Global catastrophic biological risks: Nature and response4. Surveillance policies, levels, patterns, and techniques5. The emerging pathogens: Nature, status, and threat6. Non-microbial biothreats: DNA, prions, and (bio)regulators/(bio)toxins7. Public health microbiomicsPart II. The Perpetrated Biothreat: Bioterrorism, Biocrime, and Biowarfare8. Bio-offense: Black biology9. Bio-offense: Technical means, tactical approaches, operational orientations, and strategic conceptsPart III. Biodefense Response and Intervention10. Biodefense response: Cognition and diagnosis11. Bio-defence build 2.0: The muscle12. The genomic dimension in biodefense: Therapeutics13. The genomic dimension in biodefense: Decontamination14. Regulation and legislation15. Epilogue: Resilience and preparedness, the case study of the United States