Genomics and Precision Healthcare

Nyhet

Innovations, Applications and Challenges

Inbunden, Engelska, 2026

AvSwetha Kumari Koduru,Sarad Pawar Naik Bukke,Hussaini Bello,Muhamad Mustafa Mundu,Ayush Madan

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Unlock the future of individualized patient care with this guide to mastering the interdisciplinary synergy of next-generation sequencing, clinical diagnostics, and ethical frameworks that define the new era of precision medicine. The field of genomics has witnessed remarkable growth over the past few decades, fundamentally altering the landscape of healthcare and medical research. The rapid advancement of genomic technologies, particularly next-generation sequencing and the growing understanding of the human genome, has opened new frontiers in diagnostics, treatment, and prevention. Genomics now sits at the intersection of molecular biology, bioinformatics, pharmacology, and clinical medicine, forming the foundation of precision healthcare. This book explores the transformative impact of genomics on modern medicine, from foundational principles of genetics to cutting-edge clinical applications. It examines how genomic technologies are reshaping diagnosis and treatment across conditions such as cancer, rare diseases, and infectious diseases, while highlighting the rise of precision medicine—an approach that tailors therapies based on individual genetic profiles. The book also addresses key challenges in integrating genomic data into healthcare systems, including ethical considerations in genetic testing, genomic counseling, and evolving healthcare policy. With a global perspective, it provides insights into the opportunities and complexities of implementing genomic medicine across diverse healthcare environments.

Produktinformation

Utgivningsdatum2026-06-03
FormatInbunden
SpråkEngelska
Antal sidor528
FörlagJohn Wiley & Sons Inc
ISBN9781394367528

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Biovetenskap inom Naturvetenskap och teknik

Swetha Kumari Koduru, PhD is a Scientist and Research Coordinator in the Department of Pharmaceutics and Pharmaceutical Technology at Kampala International University. She has published more than ten journal articles and book chapters internationally. Her research interests include drug design, gene cloning, and agricultural entomology.Sarad Pawar Naik Bukke, PhD is an Associate Professor and Research Coordinator in the Department of Pharmaceutics and Pharmaceutical Technology at Kampala International University with more than twelve years of experience. He has published more than 90 book chapters and articles in international journals. His research focuses on drug delivery systems, soil dispersions, bilayer tablets, and microsponges.Hussaini Bello, PhD is a Professor in the Department of Pharmaceutics in the School of Pharmacy at the University of Wolverhampton. He has published several articles in international journals and conferences of repute. His research interests include drug discovery, pharmacology, and medicinal and pharmaceutical chemistry.Muhamad Mustafa Mundu, PhD is the Head of the Department of Electrical, Telecommunications and Computer Engineering in the School of Engineering and Applied Sciences at Kampala University. He has published one book and more than 45 articles in international journals and conferences. His research interests include renewable energy systems, energy storage, and satellites.Ayush Madan, PhD is an Assistant Professor in the Department of Biotechnology in the School of Research and Technology at People's University in Bhanpur, India. He has published five books, more than 90 articles and book chapters, and one patent. His research interests include computational biology and informatics, nanobiotechnology, and bioprocess engineering.

Preface xxiii1 The Fundamentals of Genetics and Genomics: A Primer for Healthcare Professionals 1K. Haripriya, Swetha Kumari Koduru and K. Nandini2 From Gene Discovery to Clinical Applications: The Journey of Genomic Research 39Bolaji Fatai Oyeyemi, Muhammad Abiodun Sulaiman, Saheedat Olabisi Dauda, Habeebat Adekilekun Oyewusi, Oluwatosin Olubunmi Oladipo and Habeebulahi Ajibola Adekilekun3 Precision Medicine: Tailoring Treatments to Genetic Profiles 67Ashok Thulluru, Goutham Yerrakula, Nawaz Mohammed, Reshma Tadipatri and Varun Srighakollapu4 Genomic Technologies in Diagnostic Medicine: Advances and Applications 97Pradeep Natarajan5 Pharmacogenomics: How Genetic Information Influences Drug Response 139G. Avinash Kumar, P. Pravallika, V. Thirumalai, Chandrashekar Thalluri and Sarad Pawar Naik Bukke6 Ethical, Legal, and Social Implications of Genomic Data in Healthcare 171M. Reddy Sailaja, Swetha Kumari Koduru and R. Venkata Raghava Reddy7 The Role of Genomics in Rare and Noncommunicable Diseases 201S.K. Abdul Rahaman, Aman Sisodia, Ananda Kumar C.H., Padmavathi Sakinala and Ajay Bommareddy8 Cancer Genomics: Innovations in Diagnosis, Prognosis and Therapy 233Habeebulahi Ajibola Adekilekun, Olorunshola Dave Omodamiro, Ngozi Kalu Achi, Habeebat Adekilekun Oyewusi and Racheal Majekodunmi Omodamiro9 Genomic Research in Infectious Diseases: Impact and Advances 255Ananda Kumar Chettupalli, Aman Sisodia, Rajendra Kumar Jadi, Akiful Haq and Nagarani Kagithala10 Genomics of Prenatal and Paediatric Diseases: Early Detection and Intervention 295Priyanka and Ayush Madan11 Integrating Genomic Data into Electronic Health Records (EHRs) 351Raju C., Thrisha Lakkireddy, Reddi Mohan Naidu K., Sivasubramanyam Medasani and Bukke Pasunath Naik12 Genomic Counseling: Navigating the Complexities of Genetic Risk and Inheritance 373Mudigubba Manoj Kumar, Queeni Sharoon Melam, Mohammed Azhar Hussain, Vishnuvara V. Tummeeti and Akkiraju Sudheer13 Healthcare Policy and Genomics: Shaping the Future of Health Care Systems 419A. Revathi, B. Princy, K. Janani, M. Divya, B. Lokeshwari and P. Saranraj14 Patient Perspectives and Experiences with Genomic Testing 441Safa A. Abdalla15 Global Prospectives on Genomic Healthcare: Opportunities and Challenges 463Shaik Harun Rasheed, Kondapuram Parameshwar, G. Buela Priyanka, Laith Hamza Samein and Ravi Kumar VakkalagaddaAcknowledgment 485References 485Index 489