Genomic and Precision Medicine

Foundations, Translation, and Implementation

Inbunden, Engelska, 2016

AvGeoffrey S. Ginsburg,Huntington F Willard,USA) Ginsburg, Geoffrey S. (Chief Medical and Scientific Officer, All of Us Research Program, National Institutes of Health, Bethesda, Maryland,USA) Willard, Huntington F (Chief Scientific Officer, Genome Medical, Inc., South San Francisco, CA,Huntington F. Willard

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Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care.

The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care.

Provides a comprehensive volume on the translation and implementation of biology into health care provision
Presents succinct commentary and key learning points that will assist readers with their local needs for translation and implementation
Includes an up-to-date overview on major 'translational events' in genomic and personalized medicine, along with lessons learned

Produktinformation

Utgivningsdatum2016-12-20
Mått152 x 229 x 26 mm
Vikt770 g
FormatInbunden
SpråkEngelska
Antal sidor398
Upplaga3
FörlagElsevier Science
ISBN9780128006818

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Sjukdomar och rubbningar inom Medicin

Dr. Ginsburg is the founding Director of the Center for Applied Genomics & Precision Medicine in the Duke Institute for Genome Sciences & Policy. He is also Professor of Medicine and of Pathology at Duke University Medical Center, Professor of Biomedical Engineering at Duke Pratt School of Engineering, and Co-Director of the Duke Translational Medicine Institute. Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.

1. Application of Human Genome Information to Clinical Practice 2. Translating genome information into clinical practice and human health3. Big Data and Translational Bioinformatics Genomic and Personalized Medicine4. Designing Genome-Based Clinical Studies5. Developing the Evidence to Support Clinical Use Genomic Biomarkers as Diagnostics6. Health Risk Assessment and Family History7. Clinical Decision Support8. Implementation Science and Integration into Healthcare Systems9. Pharmacogenetics and Pharmacogenomics10. Drug Repurposing and Repositioning11. Point of Care Devices12. Overview of Policy, Ethical and Social Considerations13. Educational Issues and Strategies for Genomic Medicine 14. Regulation of Genomic Technologies15. Economic Value of Genomic Medicine16. Reimbursement17. Impact of Patents on Genomic Medicine

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