Gene Transfer Vectors for Clinical Application

Inbunden, Engelska, 2012

2 929 kr

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This volume of Methods in Enzymology looks at Gene Transfer Vectors for Clinical Application. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design.

Chapters provide an invaluable resource for academics, researchers and students alike
International board of authors
This volume covers such topics as general principles of retrovirus vector design, chronic granulomatous disease (CGD), gene therapy for blindness, and retrovirus genetic strategy and vector design

Produktinformation

Utgivningsdatum2012-04-18
Mått152 x 229 x undefined mm
Vikt920 g
FormatInbunden
SpråkEngelska
SerieMethods in Enzymology
Antal sidor440
FörlagElsevier Science
MedarbetareTheodoreC. Friedman
ISBN9780123865090

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Behandling och behandlingsmetoder inom Medicin

Preface: The successful clinical use of viral vectors for human gene therapy. General principles of retrovirus vector designStrategies for retrovirus-based correction of severe, combined immunodeficiency (SCID)Retrovirus and lentivirus vector design and methods of cell conditioningAnalysis of the clonal repertoire of gene corrected cells in gene therapyDeveloping novel lentiviral vectors into clinical productsLentivirus vectors in beta-thalassemiaGene Therapy for Chronic Granulomatous DiseaseAlternative splicing caused by lentiviral integration in the human genomeGenotoxicity assay for gene therapy vectors in tumor prone Cdkn2a-/- miceLentiviral Hematopoietic Cell Gene Therapy for X-linked AdrenoleukodystrophyRetroviral replicating vectors in cancerAdeno-associated virus vectorology, manufacturing and clinical applicationsGene Delivery To The Retina: From Mouse To ManGeneration of hairpin-based RNAi vectors for biological and therapeutic applicationRecombinant adeno-associated viral vector reference standardsNIH oversight of human gene transfer research involving retroviral, lentiviral and adeno-associated virus vectors and the role of the NIH recombinant DNA advisory committee draftRegulatory structures for gene therapy medicinal products in the European Union