Gene Expression and Its Discontents

The Social Production of Chronic Disease

Häftad, Engelska, 2018

Av Rodrick Wallace, Deborah Wallace

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This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis.

Produktinformation

Utgivningsdatum2018-04-29
Mått155 x 235 x 20 mm
Vikt546 g
FormatHäftad
SpråkEngelska
Antal sidor344
Upplaga2
FörlagSpringer International Publishing AG
ISBN9783319838939

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Epidemiologi och medicinsk statistik inom Medicin
Samhällsmedicin och preventiv medicin inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik

Rodrick Wallace PhD is a research scientist at the New York State Psychiatric Institute, received his B.S. in mathematics and a Ph.D. in physics from Columbia University.. A recipient of an Investigator Award in Health Policy Research from The Robert Wood Johnson Foundation. He has published many papers adapting quantitative methods from population, community and ecosystem ecology to the theoretical and empirical analysis of problems of public health and public order. Recently he has attempted to adapt methods from information theory to the study of evolutionary process in medical sociology, biology and economics.

Introduction.- 1. Toward new tools.- 2. Models of development.- 3. Groupoid symmetries.- 4. Epigenetic catalysis.- 5. Developmental disorders.- 6. An interim perspective.- 7. The obesity pandemic in the US.- 8. Coronary heart disease in the US. - 9. Cancer: a developmental perspective.- 10. Autoimmune disorders.- 11. Demoralization and obesity in Upper Manhattan.- 12. Death at an early age: AIDS and related mortality in New York City.- 13. Mental Disorders I: Western atomism and its culture-bound syndromes.- 14. Mental Disorders II: Psychopathology and sleep.- 15. Diabetes and Thyroid Cancer in Manhattan's Chinatown.- 16. Right-To-Work Laws and Alzheimer's Disease.- 17. Stress as an Environmental Exposure.- 18. Final Thoughts.- 19. Mathematical Appendix.