Gene Delivery

Nanotechnology and Therapeutic Applications

Inbunden, Engelska, 2022

AvYashwant Pathak,USA) Pathak, Yashwant (USF

3 449 kr

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Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers.Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery. Additional features include" Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing. Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize. Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario Discusses siRNA, mRNA, and DNA plasmids.

Produktinformation

Utgivningsdatum2022-06-29
Mått178 x 254 x 18 mm
Vikt620 g
FormatInbunden
SpråkEngelska
SerieDrugs and the Pharmaceutical Sciences
Antal sidor232
FörlagTaylor & Francis Ltd
ISBN9781032025544

Tillhör följande kategorier

Kemi inom Naturvetenskap och teknik
Tillverkningsteknik inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Medicin: icke kliniska discipliner inom Medicin
Farmakologi inom Medicin

Dr. Yashwant Pathak completed his Ph.D. in Pharmaceutical Technology from Nagpur University,India and his EMBA MS in Conflict Management from Sullivan University. He is Professor andAssociate Dean for Faculty Affairs at the College of Pharmacy, University of South Florida. Tampa,Florida. With extensive experience in academia as well as industry, he has more than 100 publications,two patents and two patent applications, twenty edited books published, including seven booksin Nanotechnology and six in Nutraceuticals and drug delivery systems. He has several books in culturalstudies and conflict management. He has received several National and International awards.His recent assignment was Fulbright Senior Fellow in Indonesia for six months, where he traveledin seven countries and lectured in more than twenty universities. He was a key note speaker at theWorld Hindu Wisdom meeting in Bali, Indonesia, in June 2017 and co-chaired with the Governorof Bali. Dr Yashwant Pathak is also a Professor of Global Health with the College of Public Healthat USF. Recently, his student completed a PhD in Global Health on homeopathy medicine and itsefficacy, a survey of 1274 patients in Pune in India. Dr Pathak is also an adjunct faculty member atAirLangga University College of Public Health at Surabaya Indonesia.

Chapter 01Challenges in delivering gene therapyChapter 02Advances in genome editing: the technology of choice for precise and efficient disease treatment, with special focus on nano delivery systemsChapter 03Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapyChapter 04Green nanoparticles for oligonucleotide deliveryChapter 05Development of mRNA vaccines for Covid -19 in challenging Pandemic scenarioChapter 06Gene therapy for cardiovascular diseases: clinical evidencesChapter 07Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDSChapter 08siRNA delivery for therapeutic applications using nanoparticlesChapter 09Clinical perspectives on Gene therapy for retina and eye diseasesChapter 10Herpesvirus microRNAs for use in gene therapy immune-evasion strategiesChapter 11siRNA delivery for therapeutic applications using nanoparticlesChapter 12Gene therapy and small molecule treatment for cystic fibrosisChapter 13CRISPR gene therapy recent trends and clinical applicationsChapter 14Clinical applications of gene therapy for Immuno-deficienciesChapter 15Regulatory challenges for nano gene delivery

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