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Gamma-Glutamyl Transpeptidases (?-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the ?-glutamyl amide bond of glutathione to liberate cysteinylglycine.
1 Introduction.- 2 Occurrence, genes and gene expression.- 3 Structure and function of γ-GTs.- 4 Autoprocessing and reaction mechanism of γ-GTs.- 5 γ-GT in bioclinical.- 6 γ-GTs: biotechnological and biomedical applications.- 7 Conclusions.- References.