G Protein Signaling Pathways in Health and Disease

Dr. Ya-Xiong Tao is currently Professor of Physiology at Auburn University College of Veterinary Medicine in Auburn, Alabama, USA. He has been working on several G protein-coupled receptors, including gonadotropin receptors regulating reproduction, and melanocortin receptors regulating energy and glucose homeostasis. He has published extensively in peer-reviewed biomedical journals and obtained funding for his research from National Institutes of Health, American Diabetes Association and American Heart Association, among others. He has delivered numerous lectures at universities and research institutes in USA, Canada, China, India, and Mexico. He has edited ten volumes, including seven volumes in Progress in Molecular Biology and Translational Science. He teaches several courses, including Physiology, Receptorology, Genomics and Personalized Medicine, and Molecular Endocrinology, for veterinarian, graduate, and undergraduate Honors students.

• 1. Introduction to G protein signaling pathwaysYa-Xiong Tao2. Diseases associated with mutations in CNGA3Qingjiong Zhang3. Mutations in arrestinsVsevolod V. Gurevich4. Diseases caused by mutations in GPR101Ya-Xiong Tao5. Diseases caused by mutations in lutropin receptorJie Qiao6. Beta3-adrenergic receptor polymorphism and type 2 diabetesYa-Xiong Tao7. Chemokine receptor mutations and susceptibility to HIV infectionYi-Qun Kuang8. GPR154 mutations and asthmaYa-Xiong Tao9. Diseases associated with mutations in prokineticin receptor-2 geneJia-Da Li10. Therapeutic options for loss-of-function mutations in GPCRsWei Wang11. GPCRs and primary ciliaYa-Xiong Tao