Fungal Infections in the Immunocompromised Patient

John R. Wingard, Elias J. Anaissie

• Host Defenses. Host Defenses against Fungal Pathogens. Epidemiology, Risk Factors, and Diagnostic and Management Considerations in Key At Risk Patient Populations. Solid Organ Transplant Recipients. Blood and Marrow Transplant Recipients. Oncology Patients. HIV Patients. Critical Care Patients. Pediatric Patients. Clinical Presentations of Invasive Fungal Infecgtions. Clinical Manifestations of Fungal Infections. Clinical Syndromes of Major Fungal Pathogens. Invasive Candida Infections. Invasive Aspergillus Infections. Endemic Mycoses. Emerging Pathogens. Diagnostic Methodology. Cultural and Histologic Methods. Nonivasive Diagnostic serologic and PCR Methods. Radiological Procedures. Antifungal Agents. Polyenes. Azoles. Echinocandins. Other Classes of Antifungal Agents. Drug Interactions and Specific Toxicities. Adjunctive Treatment Approaches. Treatment Strategies. Prophylaxis. Empirical Therapy of Suspected Infections. Treatment of Established Infections