Dr. Balachandar Vellingiri currently is investigating various neurological diseases and developing human induced pluripotent stem cells (HiPSCs). Exploring the cutting-edge molecular, cellular, and translational neuroscience approaches, he aims to unravel disease mechanisms, identify therapeutic targets, and develop innovative interventions to slow or reverse neurological diseases. His expertise is on several techniques such as molecular cytogenetics, pathway analysis, and techniques in developing HiPSCs and Brain organoids, especially for neurological diseases. Dr. Mahalaxmi Balachandar is currently an Assistant Professor in the Department of Community Medicine and Health, School of Health Sciences, Central University of Punjab, Punjab currently involved in handling neurological disorder patients and conducting genetic and epigenetic studies. Her expertise is in handling bone marrow derived mesenchymal stem cells (BM-MSCs) as a promising therapeutic agent for LHON disease.

• Section I An overview about Organoids1. An overview on organoids - Past, present and future scenario of organoidsSection II Neurodevelopmental disorder2. A brief introduction about neurodevelopmental disorders3. Use of brain organoids for autism4. Role of brain organoids in Rett Syndrome5. Brain organoids in bipolar disorder: Unraveling mechanisms and therapeutic approaches6. Ongoing clinical trials on use of brain organoids for neurodevelopmental disordersSection III Neurodegenerative diseases7. An overview of Neurodegenerative diseases8. Use of brain organoids for Parkinson’s disease and Alzheimer’s disease9. Application of brain organoids in Huntington’s disease10. Ongoing clinical trials on use of brain organoids for neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc.)Section IV Methods involved in organoids development11. How human-induced pluripotent stem cells are derived into organoids12. Elements required and days involved in organoid generationSection V – Application and advancement of Brain organoids13. Brain organoids – Challenges while constructing organoids14. Existing drug targeting and research using brain organoidsSection VI - Ethical consideration while conducting organoids research15. Ethical consideration while conducting organoids researchSection VII - Future perspective and concluding remarks16. Future directions and conclusion

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