Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Inbunden, Engelska, 2013

AvAlexander A. Vinks,Hartmut Derendorf,Johan W. Mouton

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The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Produktinformation

Utgivningsdatum2013-11-24
Mått155 x 235 x 31 mm
Vikt842 g
FormatInbunden
SpråkEngelska
Antal sidor466
Upplaga2012
FörlagSpringer-Verlag New York Inc.
ISBN9780387756127

Tillhör följande kategorier

Onkologi inom Medicin
Infektionssjukdomar och smittsamma sjukdomar inom Medicin
Farmakologi inom Medicin
Samhällsmedicin och preventiv medicin inom Medicin
Patologi inom Medicin

Foreword.- Section I: Basic Concepts and Principles.- Introduction to Pharmacodynamics and micrbiology.- In vitro and animal PK/PD model.- MIC and breakpoints.- Principles of applied PK/PD modeling.- Population Pk/PD modeling and its applications to antimicrobials.- Drug resistance and Drug-drug combinations.- Section II: Clinical.- Aminoglycosides.- Beta-lactam antibiotics including continuous infusion.- Macrolides.- Glycopeptides.- Quinolones.- Other.-

From the reviews: "The book's first half can function as an advanced textbook and support learning these concepts and principles. The level and presentation are appropriate for learners who already have a reasonable grasp of general pharmacokinetics and pharmacodynamics, such as advanced graduate students, medical students, or pharmacy students. ... The second half applies these principles to an in-depth analysis of pharmacokinetics/pharmacodynamics for classes of antimicrobial drugs. This treatment can enhance the understanding and the application of these concepts for even experienced practitioners." (Gregory Reed, Doody's Book Reviews, June, 2014)