Häftad, Engelska, 2011

Functioning of Transmembrane Receptors in Signaling Mechanisms

Cell Signaling Collection

Av Ralph A. Bradshaw, Edward A. Dennis

969 kr

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Beskrivning

A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. Written and edited by experts in the field, this book provides up-to-date research on transmembrane signaling entities and their initiating responses following extracellular stimulation.

Articles written and edited by experts in the field
Thematic volume covering effectors, cytosolic events, nuclear, and cytoplasmic events
Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

Produktinformation

Utgivningsdatum: 2011-04-05
Mått: 216 x 276 x 23 mm
Vikt: 1 330 g
Format: Häftad
Språk: Engelska
Antal sidor: 456
Förlag: Elsevier Science
ISBN: 9780123822116

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Mer information

Ralph A. Bradshaw is Professor Emeritus in the Department of Physiology and Biophysics at the University of California, Irvine. Prior to that he was on the faculty of the Department of Biological Chemistry, Washington University, and Professor and Chair of the Department of Biological Chemistry, University of California Irvine. He presently is Professor of Pharmacology at the University of California, San Diego. He served as president of FASEB, was the founding president of the Protein Society and was the treasurer of the ASBMB. He was the founding editor of Molecular and Cellular Proteomics. His research has focused on protein chemistry and proteomics, with emphasis on the structure and function of growth factors and their receptors, particularly nerve growth factor and ﬁbroblast growth factor, and the involvement of receptor tyrosine kinases in cell signaling. He has also studied the role of proteolytic processing and N-terminal modiﬁcation in protein stability and turnover. Edward A. Dennis is Distinguished Professor and former Chair of the Department of Chemistry and Biochemistry and Professor in the Department of Pharmacology in the School of Medicine at the University of California, San Diego. He is also Editor-in-Chief of the Journal of Lipid Research.

Recensioner i media

"This volume reprints 53 articles originally published in by Elsevier in 2010. The researchers describe the structure and role of cell surface receptors in signaling activities with separate sections on tyrosine kinase, cytokine, G protein-coupled, TGFB, TNF, and immunoglobin receptors. The opening chapters review the chemical principles of protein binding, FRET detection techniques, protein tyrosine phosphatases, and the formation of oligomers. Color figures are provided." --Reference and Research Book News

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