Del 33 - Methods in Microbiology

Functional Microbial Genomics

Inbunden, Engelska, 2002

2 729 kr

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Functional Microbial Genomics, edited by two leading experts in the field, provides the researcher with an up-to-date collection of articles on post-genome technologies central to studying the function of microorganisms.Since the release of the first complete genome sequence of a free-living organism in 1995, over 100 microbial genomes have been completely sequenced. The advent of new technologies for post-genomic analyses has allowed the rapid exploitation of this genome sequence information, heralding a golden era in microbial research. Functional Microbial Genomics provides in-depth accounts from scientists working with these new technologies explaining both the techniques and the ways in which they have been applied to the study of gene function in different microbial species.Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research.

* Bioinformatic approaches to genome sequence analysis* Details the design, construction and applications of DNA microarrays* Covers advances in bacterial proteome and metagenome analysis* Describes functional genomic approaches for novel antibiotic target and vaccine candidate discovery* Presents case studies where functional genomic analyses have revolutionized our understanding of model species

Produktinformation

Utgivningsdatum2002-12-12
Mått169 x 244 x 0 mm
Vikt1 000 g
FormatInbunden
SpråkEngelska
SerieMethods in Microbiology
Antal sidor428
FörlagElsevier Science
ISBN9780125215336

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik

GENOME SEQUENCE ANALYSISAnnotation of genomes From sequence to consequence: in silico hypothesis generation and testingThe atlas visualisation of genome-wide informationCONSTRUCTION OF DNA MICROARRAYSMicroarray design for bacterial genomesGlass slides microarrays for bacterial genomesCOMPARAIVE NUCLEIC ACID ANALYSIS Representational display analysis of Cdna and genome comparisonsApplication of DNA microarrays for comparative and evolutionary genomicsGene expression during host-pathogen interactions: approaches to bacterial mRNA extraction and labelling for microarray analysisHigh throughput in vivo screens: signature-tagged mutagenesisFurther strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantitation of DNA-tagged strainsPROTEOME ANALYSISAdvances in bacterial proteome analysisDiscovery of protein-protein interaction using two-hybrid systemsSECTION V APPLICATIONS OF MICROBIAL GENOMICS Cloning the metagenome: Culture-independent access to the diversity and functions of the uncultivated microbial worldReverse vaccinology: from genome to vaccineMicrobial genomics for antibiotic target discovery CASE STUDIES - BACTERIAHelicobacter pylori functional genomicsStreptomyces coelicolor A3(2): from genome sequence to functionFunctional analysis of the Bacillus subtilis genomeSECTION VII CASE STUDIES - PARASITESPlasmodium falciparum DNA microarrays and interpretation of dataFunctional analysis of the Plasmodium falciparum genome using transfectionChromosome fragmentation as an approach to whole genome analysis in trypanosomes

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