Formulation

Anne-Marie Pensé-Lhéritier works for École de Biologie Industrielle (EBI) in Cergy, France.

• Preface xiPART ONE: GENERAL INFORMATION 1Chapter 1. Introduction 3André CHEYMOL1.1. Definition 31.2. Historical background 31.3. From art to science 81.4. Overview of the economical impact of the aforementioned products 141.5. Book presentation and structure 151.6. Bibliography 16Chapter 2. Formulation in Major Organic Chemistry Industries 19André CHEYMOL2.1. Necessity and concept 192.2. Factors affecting different industries 262.3. Outlining a methodology 272.4. Bibliography 30PART TWO: CONCEPT AND APPLICATION 31Chapter 3. Solutions 33Anne-Marie PENSÉ-LHÉRITIER3.1. Introduction 333.2. Solubilizing in water 353.3. Solubilizing in solvents 373.4. Processes to help solubilization 433.5. Conclusion 483.6. Bibliography 49Chapter 4. Dispersions 53Gérard HOLTZINGER4.1. Introduction 534.2. Particles and their specificities 544.3. Various particle systems and stability issues 624.4. Dispersion methods and analysis techniques 894.5. Rheology 1074.6. Bibliography 115Chapter 5. Formulation of Emulsions 119Anne-Marie PENSÉ-LHÉRITIER5.1. General aspects of emulsions 1195.2. Theoretical considerations on the liquid–liquid interactions 1215.3. Developing the emulsion 1255.4. Stabilizing an emulsion 1345.5. Formulation of emulsions 1415.6. Conclusion 1445.7. Bibliography 144Chapter 6. Suspensions 147Gérard HOLTZINGER6.1. Dispersion theory 1486.2. Formulation of suspensions 1556.3. Stability agents of suspensions 1586.4. Specific case of the pharmaceutical realization 1646.5. Specific case of cosmetics 1646.6. Using dispersion 1676.7. Bibliography 183Chapter 7. Dispersions in High-Viscosity Mediums: Formulating Polymers 185André CHEYMOL7.1. Characterization of polymers 1857.2. Formulation of polymers: general information 1987.3. Thermal behavior 2117.4. Heat generation and transmission 2167.5. Main mixing tools 2187.6. Conclusion on the polymer formulation rules 2277.7. Bibliography 227PART THREE: FORMULATION OF MAJOR PRODUCTS 231Chapter 8. Dosage Form and Pharmaceutical Development 233Vincent FAIVRE8.1. Drugs development 2338.2. Case study: development of a dosage form for oral administration 2468.3. Monitoring/checking methods 2498.4. Bibliography 252Chapter 9. Formulation of Cosmetic Products 253Caroline ROUSSEAU9.1. Introduction 2539.2. Specifications 2549.3. Development in the laboratory 2569.4. Industrial fabrication 2659.5. Product launch 2659.6. Regulations 2669.7. Conclusion 267Chapter 10. Formulation of Food Products 269Christine CHÊNÉ10.1. Specifications 26910.2. Constraints 27110.3. Formulation methodology 279Chapter 11. Formulation of Elastomers 283André CHEYMOL11.1. Introduction 28311.2. Choice of the elastomers 28411.3. Adjuvants required to obtain crucial functions 29011.4. Formulation realization: mixture 31211.5. Conclusion 31711.6. Bibliography 318Conclusion 321List of Authors 323Index 325