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Formulating Poorly Water Soluble Drugs

Häftad, Engelska, 2023

Av Robert O. Williams III, Daniel A. Davis Jr., Dave A. Miller, Daniel A. Davis Jr

3 309 kr

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The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

Produktinformation

  • Utgivningsdatum2023-05-20
  • Mått178 x 254 x undefined mm
  • FormatHäftad
  • SpråkEngelska
  • SerieAAPS Advances in the Pharmaceutical Sciences Series
  • Antal sidor693
  • Upplaga3
  • FörlagSpringer Nature Switzerland AG
  • ISBN9783030887216

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