Flow Cytometry in Hematolymphoid Neoplasms

Dr Wei Wang, MD, Ph.D., an Associate Professor in the Department of Hematopathology at MD Anderson Cancer Center, has authored over 200 peer-reviewed publications, with a strong focus on flow cytometry in the diagnosis of hematopoietic neoplasms. He also contributed as a co-author to the 5th edition WHO classification of hematopoietic neoplasms. Dr. Sa A. Wang is a Professor of Pathology and Section Chief of Flow Cytometry at MD Anderson Cancer Center. A global leader in hematopathology, she specializes in diagnosing hematolymphoid neoplasms through flow cytometry, histopathology, and molecular genetics. Dr. Wang has authored over 300 scientific articles and co-edited multiple landmark texts in the field. She currently serves as President of the International Clinical Cytometry Society and associate editor of Cytometry B Clinical Cytometry.

• Section I. Mature B-Cell and Plasma Cell Neoplasms; 1. B-Cells: normal maturation and strategies in identification of abnormal cells Wei Wang; 2. Chronic lymphocytic leukemia/small lymphocytic lymphoma and mantle cell lymphoma Wei Wang; 3. Follicular lymphoma Wei Wang; 4. Low-grade b-cell lymphomas with plasmacytic differentiation Andres E Quesada and Pei Lin; 5. Splenic b-cell lymphoma/leukemia (other than splenic marginal zone lymphoma) and b-cell prolymphocytic leukemia Beenu Thakral and Sa A Wang; 6. Aggressive b-cell lymphomas Shaoying Li, Jie Xu and Lianqun Qiu; 7. Large b-cell lymphoma with plasmablastic differentiation Lianqun Qiu, Shaoying Lin, Pei Lin, Jiehao Zhou, Yi Zhou and Jie Xu; 8. Plasma cell neoplasms Andres E Quesada and Pei Lin; Section II. Mature T-Cell and Nk-Cell Neoplasms; 9. T and NK cells: normal maturation and strategies in identification of abnormal cells Wei Wang; 10. T-cell large granular lympocytic leukemia Min Shi, Michael M. Timm and Dragan Jevremovic; 11. Hepatosplenic T-cell lymphoma Min Shi, Michael M. Timm and Dragan Jevremovic; 12. Adult T-cell leukemia/lymphoma Hong Fang and Wei Wang; 13. T-prolymphocytic leukemia Hong Fang and Wei Wang; 14. Mycosis fungoides/ Sezary syndrome Hong Fang and Wei Wang; 15. NK-Large granular lympocytic leukemia Min Shi, Michael M. Timm and Dragan Jevremovic; 16. Aggressive NK-cell leukemia Min Shi, Michael M. Timm and Dragan Jevremovic; 17. Nodal T follicular helper cell lymphoma Chi Young Ok, Francisco Vega and Sa A. Wang; 18. Anaplastic large cell lymphoma, ALK-positive Jie Xu, Shaoying Li and L. Jeffrey Medeiros; 19. Anaplastic large cell lymphoma, ALK-negative Jie Xu, Jeffrey Medeiros and Shaoying Li; 20. Other nodal and extranodal mature T/NK-cell lymphomas Chi Young Ok, Francisco Vega and Sa A. Wang; Section III. Acute Lymphoblastic Leukemia/Lymphoma; 21. B-lymphopblastic leukemia/lymphoma Sa A. Wang; 22. T-lymphopblastic leukemia/lymphoma Sa A. Wang; Section IV. Acute Myeloid Leukemia; 23. Acute myeloid leukemia: introduction Wei Wang; 24. Acute myeloid leukemia with RUNX1: RUNX1T1 fusion Wei Wang; 25. Acute myeloid leukemia with CBFB rearrangement Wei Wang; 26. Acute promyelocytic leukemia Hong Fang and Wei Wang; 27. Acute myeloid leukemia with NPM1 mutation Wei Wang; 28. Acute myeloid leukemia with KMT2A rearrangement Wei Wang; 29. Acute myeloid leukemia with MECOM rearrangement Wei Wang; 30. Acute myeloid leukemia with DEK: NUP214 fusion Wei Wang; 31. Acute myeloid leukemia with NUP98 rearrangement Mahsa Khanlari and Wei Wang; 32. Acute myeloid leukemia with mutated TP53 Fnu Sameeta and Wei Wang; 33. Acute erythroid leukemia Wei Wang; 34. Acute megakaryoblastic leukemia Mahsa Khanlari and Wei Wang; 35. Normal myelomonocytic maturation and evaluation of acute myeloid leukemia minimal/measurable residual disease Wei Wang and Sa A. Wang; Section V. Acute Leukemias of Mixed or Ambiguous Lineage; 36. Acute undifferentiated leukemia Vasiliki Leventaki and Sa A. Wang; 37. Mixed-phenotype acute leukemia Vasiliki Leventaki and Sa A Wang; Section VI. Neoplastic Plasmacytoid Dendritic Cell Proliferation; 38. Plasmacytoid dendritic cells: from normal maturation to neoplastic proliferations Wei Wang; Section VII. Other Myeloid Neoplasms and Bone Marrow Failure Diseases; 39. Chronic myeloid neoplasms and bone marrow failure disorders Sanam Loghavi, Sa A. Wang and Wei Wang; 40. Systemic mastocytosis Wei Wang, Jie Xu, Sa A. Wang, Lianqun Qiu and Shaoying Li; Section VIII. Flow Cytometry Data Handling; 41. Flow cytometry data processing, analysis, artifacts and pitfalls Xuehai Wang; Section IX. Chimeric Antigen Receptor (Car) T-Cell; 42. Chimeric antigen receptor (CAR) T-Cell immunotherapy and flow cytometric monitoring of CAR T-cells Jianhua Ling and Sa A. Wang; Appendix: common flow cytometry markers and their utility.