Fifty Years of Magnetoencephalography

Andrew C. Papanicolaou is Professor of Clinical Neuroscience Emeritus of the University of Tennessee, College of Medicine, where he served as founder and Chief of the Division of Clinical Neuroscience; visiting Professor of Neurology at the National University of Athens, Greece; President of the advisory board of the Center of Applied Neuroscience of the University of Cyprus and honorary member of the Hellenic Clinical Neurophysiology and Neuropsychology Societies. Timothy P.L. Roberts is a Professor of Radiology at the Children's Hospital of Philadelphia, University of Pennsylvania. He received his BA from Cambridge University in 1988 and his PhD, also from Cambridge University, in 1992. He has developed a career in multimodal neuroimaging, especially using MEG, MRI, and MRS and been on the faculty at UCSF and the University of Toronto before his arrival at CHOP/University of Pennsylvania in 2005. James W. Wheless is a Diplomate of the American Board of Pediatrics, and theAmerican Board of Psychiatry and Neurology with special qualifications in Child Neurology, Clinical Neurophysiology, and Epilepsy. He is a fellow of the American Academy of Pediatrics, the American College of Pediatrics, the American Academy of Neurology, and the American Epilepsy Society. Dr. Wheless is a member of the Editorial Board for the Journal of Child Neurology, Formulary, and Epilepsy.com and serves as reviewer of a number of journals including: Neurology, Epilepsia, Pediatrics, and Epilepsy and Behavior.

• PREFACE Section One: The Beginnings 1. THE FIRST MEG REPORT: 1968David Cohen Massachusetts Institute of Technology 2. THE BEGINNING OF BIOMAGNETISM AND MEG RESEARCH IN FINLAND IN THE 1970sToivo KatilaHelsinki University of Technology 3. A VIEW FROM NEAR THE BEGINNING OF MEG: AFTER HALF A CENTURYLloyd KaufmanNew York University Section Two: Technical Advances 4. PHYSIOLOGICAL BASES OF MEG AND EEGYoshio OkadaBoston Children's Hospital and Harvard Medical School 5. WHICH PART OF THE NEURONAL CURRENT CAN BE DETERMINED BY EEG?A.S. Fokas, P Hashemzadeh and R. LeahyUniversity of Cambridge and University of Southern California 6. MEG SOURCE ESTIMATION: TRANSFORMING THE SENSOR-LEVEL SIGNALS TO ESTIMATES OF BRAIN ACTIVITYMatti S. HämäläinenMassachusetts General Hospital and Harvard Medical School7. The Need for and the Road to Hybrid MEG-MRIRisto J. IlmoniemiAalto University School of Science 8. MAGNETOENCEPHALOGRAPHY USING OPTICALLY PUMPED MAGNETOMETERSElena Boto, Niall Holmes, Tim Tierney, James Leggett, Ryan Hill, Stephanie Mellor, Gillian Roberts, Gareth Barnes, Richard Bowtell and Matt BrookesUniversity of Nottingham and the Wellcome Trust Centre for Neuroimaging, University College London Section Three: Applications to Epilepsy 9. GUIDELINES AND PRACTICAL CONSIDERATIONS FOR MAPPING EPILEPTIFORM ACTIVITY WITH MAGNETOENCEPHALOGRAPHYRoozbeh Rezaie, James W. Wheless, and Abbas Babajani-Feremi.The University of Tennessee Health Science Center 10. BEYOND THE IRRITATIVE ZONE: USE OF MEG TO CHARACTERIZE ASPECTS OF THE EPILEPTOGENIC ZONEEduardo M. Castillo, Tara Kleineschay, Milena Korostenskaja , James Baumgartner and Ki Hyeong Lee Florida Hospital for Children 11. USE OF MULTIPLE FREQUENCY BANDS IN MEG FOR CHARACTERIZATION OF EPILEPSYWoorim Jeong and Chun Kee Chung Seoul National University 12. CAN MAGNETOENCEPHALOGRAPHY IDENTIFY THE EPILEPTOGENIC PATHOLOGY IN CHILDREN?Won Seok Chang and Hiroshi OtsuboThe Hospital for Sick Children, University of Toronto 13. REVISIONAL ANALYSIS OF EEG AND MEG BASED ON COMPREHENSIVE EPILEPSY CONFERENCENobukazu Nakasato, Akitake Kanno, Makoto Ishida, Shin-ichiro Osawa, Masaki Iwasaki, Yosuke Kakisaka and Kazutaka JinTohoku University Graduate School of Medicine 14. EPILEPTIC SLOW WAVE ACTIVITYStefan Rampp and Martin KaltenhäuserUniversity Hospital, Erlangen University Section Four: Somatosensory, Motor and Language Mapping 15. CLINICAL MOTOR MAPPING WITH MEG: HISTORICAL APPROACHES, CHALLENGES AND RECOMMENDATIONS FOR BEST PRACTICEWilliam Gaetz, PhD. The Children's Hospital of Philadelphia, University of PennsylvaniaChristos Papadelis, Boston Children's Hospital, Harvard Medical School andTony Wilson, University of Nebraska Medical Center 16. INVESTIGATIONS OF THE SOMATOSENSORY SYSTEM WITH MEG: FROM RESEARCH TO CLINICAL APPLICATIONSXavier De Tiègeand Hôpital Erasme, Université libre de Bruxelles andVeikko Jousmäki, Aalto University School of Science and Nanyang Technological University 17. LANGUAGE MAPPING WITH MEG: CLINICAL AND RESEARCH APPLICATIONSPanagiotis G. SimosUniversity of Crete, School of Medicine Susan M. BowyerHenry Ford Hospital and Wayne State UniversityKyousuke KamadaAsahikawa Medical University Section Five: Exploring the Brain Mechanisms of Cognition 18. READING, READING ACQUISITION AND READING DISABILITY (DYSLEXIA) Panagiotis G. SimosUniversity of Crete School of Medicine 19. MEG DECODING COGNITIVE FUNCTION WITH MEGDimitrios PantazisMassachusetts Institute of Technology 20. HOW BRAIN RHYTHMS REFLECT COGNITIVE PROCESSESJoachim GrossWestphalian-Wilhelms-University of Muenster Section Six: Neuronal Correlates of Cognitive and Affective Disorders 21. APPLICATIONS OF MEG TO AUTISM SPECTRUM DISORDERKristina Safar, Margot J. Taylor, Hospital for Sick Children, Toronto Junko Matsuzaki and Timothy P.L. RobertsChildren's Hospital of Philadelphia 22. FUNCTIONAL WOUNDS OF AN INVISIBLE INJURY: VISUALIZING COGNITION IN PTSDBenjamin T. Dunkley and Margot J. TaylorHospital for Sick Children, University of Toronto 23. IDENTIFYING NEURAL ABNORMALITIES IN SCHIZOPHRENIAJ. Christopher Edgar Children's Hospital of Philadelphia and Gregory A. MillerUniversity of California, Los Angeles 24. BIOMARKERS IN PEDIATRIC MEGJulia M. Stephen, Isabel Solis, John F.L. Pinner, Felicha T. Candelaria-CookThe Mind Research Network, Lovelace Biomedical and Environmental Research Instituteand The University of New Mexico 25. MAGNETOENCEPHALOGRAPHY IN Alzheimer's disease: CORRELATION WITH CURRENT BIOMARKERSDavid López-Sanz; Jaisalmer de Frutos-Lucas; Gianluca Susi, and Fernando Maestú, Complutense University of Madrid POSTSCRIPT