Field Flow Fractionation

Nyhet

Principles and Applications

Inbunden, Engelska, 2025

Av Céline Guéguen, Mohammed Baalousha, Kim R. Williams, Celine Gueguen

2 069 kr

Kommande

Comprehensive, up-to-date, and user-centered one-stop reference on principles and applications of Field flow fractionation (FFF), a highly versatile separation technology Field Flow Fractionation Principles and Applications offers a comprehensive and topical one-stop reference on field flow fractionation (FFF), an important separation technique which has been proven successful in the analysis of natural and engineered nanoparticles, pharmaceuticals, proteins, polymers, soils, and food. After introductory chapters on theory, principles, and instrumentation, a tutorial-style user guide addresses typical users' questions and problems. In the application part, the separation of all relevant particle classes is discussed by international experts. Sample topics covered in Field Flow Fractionation Principles and Applications include: Historical perspectives of the technique, normal versus steric versus hyperlayer modes, retention resolution, and fractionation powerFFF techniques, including flow (asymmetric, frit inlet, and outlet), sedimentation, thermal, electric, and other novel techniques such as 2DHow to determine if FFF is the correct choice and if it is being implemented correctly, along with general optimization strategies including carrier fluid, calibration, and reproducibilitySample overloading and recovery, detector selection, troubleshooting, and performance of other fractionation techniquesBoth beginners and experienced chemists and researchers can confidently rely on Field Flow Fractionation Principles and Applications to confirm their own understanding and to improve their FFF methods and interpretation of their results.

Produktinformation

Utgivningsdatum2025-12-10
Mått170 x 244 x undefined mm
FormatInbunden
SpråkEngelska
Antal sidor288
FörlagWiley-VCH Verlag GmbH
ISBN9783527340682

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Biologi inom Naturvetenskap och teknik

Celine Gueguen, PhD, is Professor of Chemistry and Canada Research Chair in Aquatic Science and Biogeochemistry at Trent University, where she has been actively involved in teaching and research since 2007. Mohammed Baalousha, PhD, has been Assistant Professor of Environmental Nanoscience at the University of South Carolina, USA, since 2014. Kim R. Williams is Professor of Chemistry and the Director of the Laboratory for Advanced Separations Technologies at the Colorado School of Mines.

PART I: THEORYChapter 1. The Basics FFF OverviewHistorical perspectives Normal vs steric vs hyperlayer modes RetentionResolution, fractionation powerChapter 2. FFF techniquesAF4 -Flow FFF (asymmetric, frit inlet and outlet)HF5- Hollow-fiber flow FFF Sedimentation FFFThermal FFFElectrical FFFNovel techniques (including 2D-FFF)Chapter 3. User guideWhich FFF is right for you?How to use FF correctly?General optimization strategies: carrier fluid, calibration, reproducibilitySample overloadingSample recoveryWhich detector to choose?How to troubleshoot FFF? (in general terms)Chapter 4. Other physical fractionation techniques: focus on performance as compared to the FFFFiltration/UltrafiltrationCentrifugation/ultracentrifugationSize exclusion chromatographyLiquid chromatographyMicrofluidicsPrecipitation PART II: APPLICATIONSChapter 5. Polymer and latexChapter 6. Biological particles: Virus, DNA/RNA, drug deliveryChapter 7. Nanoparticles in water and soilChapter 8. Manufactured nanoparticlesChapter 9. Protein, enzymesChapter 10. Cell separations - blood and algal cellsChapter 11. Food industry -StarchChapter 12. Pharmaceutical industry - drug deliveryChapter 13. Disease diagnosis