Del 382 i serien Current Topics in Microbiology and Immunology

Fc Receptors

Inbunden, Engelska, 2014

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Part IV, FcRs and Disease, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection.

Produktinformation

Utgivningsdatum2014-08-25
Mått155 x 235 x 30 mm
Vikt822 g
FormatInbunden
SpråkEngelska
SerieCurrent Topics in Microbiology and Immunology
Antal sidor424
Upplaga2014
FörlagSpringer International Publishing AG
ISBN9783319079103

Tillhör följande kategorier

Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin
Biokemi inom Naturvetenskap och teknik

The Old but New IgM Fc Receptor (FcμR).- Emerging Roles for FCRL Family Members in Lymphocyte Biology and Disease.- Intracellular antibody immunity and the cytosolic Fc receptor TRIM21.- Computational modeling of the main signaling pathways involved in mast cell activation.- Calcium channels in FcR signaling.- Regulation of FcεRI signaling by lipid phosphatases.- Fc Receptors as Adaptive Immunoreceptors.- Glycosylation and Fc Receptors.- Antibodies as natural adjuvants.- IgA, IgA receptors and their anti-inflammatory properties.- Humanized mice to study FcγR function.- FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions.- Human FcR polymorphism and disease.- Bridging auto-antibodies and arthritis; the role of Fc Receptors.- The FcγR of humans and non-human primates and their interaction with IgG: Implications for induction of inflammation, resistance to infection and the use of therapeutic monoclonal antibodies.- FcgRIIB as a key determinant of agonistic antibody efficacy.- Fc receptor dependent mechanisms of monoclonal antibody therapy of cancer; professionals at work.- Sweet and Sour: The role of glycosylation for the anti-inflammatory activity of immunoglobulin G.