Evolutionary Cell Biology of the Fetal-Maternal Interface

Günter Wagner is the Alison Richard Professor Emeritus of Ecology and Evolutionary Biology. After undergraduate education in chemical engineering, Wagner studied zoology and mathematical logic at the University of Vienna, Austria. He finished his PhD in theoretical population genetics in 1979 and conducted postdoctoral research at Max Planck Institutes in Göttingen and Tübingen, as well as at the University of Göttingen. Wagner began his academic career as assistant professor in the Theoretical Biology Department of the University of Vienna. He then moved to Yale University as a full professor of biology and has served as the first chair of Yale's Department of Ecology and Evolution. The focus of Wagner's work is on the evolution of complex characters. His research utilizes both the theoretical tools of population genetics as well as experimental approaches in evolutionary developmental biology. He has contributed substantially to the current understanding of evolvability of complex organisms, the origin of novel characters, and modularity. Günter Wagner is recipient of numerous awards, among them the prestigious MacArthur Prize, the Bobby Murcer Prize, and the Humboldt Prize. He received nominations as Gomperz Lecturer, University of California, Berkeley; Koopmans Distinguished Lecturer, IIASA Vienna; Sewall Wright Speaker, University of Chicago, IL. He is also a corresponding Member of Austrian Academy of Sciences, a Fellow of the American Association for the Advancement of Science, and a Fellow of the American Academy of Arts and Sciences. Wagner was elected to the National Academy of Sciences in 2018.Mihaela Pavličev, Univ.-Prof. Mag. Dr., Deputy Head of the Department of Evolutionary Biology, Head of the Unit for Theoretical Biology at the University of Vienna. Her research focuses upon the organismal features that enable evolvability of complex organisms. She seeeks to understand phenotypic evolution, patterns of heritable phenotypic variation in the developmental/physiological systems, and the consequences of specific patterns of variation over short terms under selection and drift.

• 1. Introduction 2. Phylogenetic and developmental context 3. The many faces of viviparity 4. On the use and misuse of the comparative method 5. Evolutionary obstacles on the way to the fetal maternal unit 6. Decidua as a novel hybrid tissue 7. Menstruation 8. “The placenta” is not a unitary character 9. The good, the bad and the ugly: the placenta-cancer-malignancy connection 10. A tapestry of evolutionary innovations: the role of historicity